Evidence map›Paper›PMID 30282879›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2019

In Vitro and In Vivo Detection of Drug-induced Apoptosis Using Annexin V-conjugated Ultrasmall Superparamagnetic Iron Oxide (USPIO): A Pilot Study.

Akihiro Nishie, Osamu Togao, Chihiro Tamura, Mayumi Yamato, Kazuhiro Ichikawa, Satoshi Nohara, Yoshio Ito, Naoki Kato, Satoshi Yoshise, Hiroshi Honda

Open access · diamondAbstract read
In one paragraph

Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Annexin Animal Models-From Fundamental Principles to Translational Research.International journal of molecular sciences · 2021
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Akihiro NishieDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
Osamu TogaoDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
Chihiro TamuraInnovation Center for Medical Redox Navigation, Kyushu University.
Mayumi YamatoInnovation Center for Medical Redox Navigation, Kyushu University.
Kazuhiro IchikawaInnovation Center for Medical Redox Navigation, Kyushu University.
Satoshi NoharaMeito Sangyo Co., Ltd.
Yoshio ItoMeito Sangyo Co., Ltd.
Naoki KatoGuerbet Japan KK.
Satoshi YoshiseGuerbet Japan KK.
Hiroshi HondaDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University.
Kyushu University · JPMeito Sangyo (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the binding potential of newly developed Annexin V-conjugated ultrasmall superparamagnetic iron oxide (V-USPIO) for detection of drug-induced apoptosis in vitro and in vivo.

methodsApoptotic cells induced by camptothecin were incubated with or without Annexin V-USPIO at a concentration of 0.089 mmol Fe/L in vitro. T

resultsThe suspension of apoptotic cells incubated with Annexin V-USPIO showed shorter T

conclusionA newly developed Annexin V-USPIO could have the potential for detection of drug-induced apoptosis.

Indexed as

ApoptosisMagnetic Resonance ImagingMagnetic Resonance SpectroscopyAnimalsAnnexin A5Antineoplastic AgentsContrast MediaCyclophosphamideDextransEtoposideFemaleHumansInjections, IntravenousIronJurkat CellsMagnetite NanoparticlesAnnexin A5Antineoplastic AgentsContrast MediaCyclophosphamideDextransEtoposideferumoxtran-10IronMagnetite NanoparticlesAnnexin V-conjugatedapoptosischemotherapymagnetic resonance imagingultrasmall superparamagnetic iron oxide

Identifiers

PMID30282879
PMCPMC6460121
OpenAlexW2895056121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.