Evidence map›Paper›PMID 30282841›Full record

ArticleThe Journal of veterinary medical science2018

Detection of neutralizing antibody against porcine epidemic diarrhea virus in subclinically infected finishing pigs.

Naoki Koike, Thi Ngan Mai, Mamoru Shirai, Meiko Kubo, Kazuhiro Hata, Nobuyuki Marumoto, Shinji Watanabe, Yosuke Sasaki, Shuya Mitoma, Kosuke Notsu and 5 more

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  6. Evaluating the Risk Factors forFrontiers in veterinary science · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Naoki KoikeDepartment of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Thi Ngan MaiGraduate School of Medicine and Veterinary Medicine, University of Miyazaki, Miyazaki 889-1692, Japan.
Mamoru ShiraiMiyakonojo Meat Inspection Office, Miyazaki 885-0021, Japan.
Meiko KuboMiyakonojo Meat Inspection Office, Miyazaki 885-0021, Japan.
Kazuhiro HataMiyakonojo Livestock Hygiene Service Center, Miyazaki 889-4505, Japan.
Nobuyuki MarumotoMiyakonojo Livestock Hygiene Service Center, Miyazaki 889-4505, Japan.
Shinji WatanabeNational Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Yosuke SasakiOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki 889-2192, Japan.
Shuya MitomaDepartment of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Kosuke NotsuDepartment of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Tamaki OkabayashiDepartment of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Anuwat WiratsudakulDepartment of Clinical Sciences and Public Health, Faculty of Veterinary Science, Mahidol University, 999 Phuttamonthon 4 Rd., Salaya, Phuttamonthon, Nakhon Pathom, 73170, Thailand.
Emmanuel KabaliQuality Assurance Unit, Director General's Office, Zambia Medicines Regulatory Authority, Plot 6903, P.O. Box 31890, Lusaka, Republic of Zambia.
Junzo NorimineDepartment of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Satoshi SekiguchiDepartment of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
University of Miyazaki · JPMatsumoto Livestock Hygiene Service Center · JPMahidol University · THNational Institute of Infectious Diseases · JPVietnam National University of Agriculture · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to detect porcine epidemic diarrhea virus (PEDV) subclinically infected pigs shipped from non-case farms to slaughterhouses. Systematic sampling was conducted at two slaughterhouses. A total of 1,556 blood samples were collected from 80 case and non-case farms from pigs over 6 months old. Blood samples were centrifuged to obtain sera. Serial serum dilutions were subjected to serological examination for PEDV presence using Neutralization test (NT). The cut-off titer was set at titer of 1:2 dilution and farms with at least one positive sample in duplicate were classified as PED-positive farms. Several non-case farms (9.4%, 6/64) and 100% (16/16) of the case farms were indeed positive for PEDV. The proportion of seropositive animals from case farms was 63.7%, significantly different from that of non-case farms (4.3%, P<0.05). In both case and non-case farms, the proportion of seropositive animals in farrow-to-finish farms was significantly higher than in wean-to-finish farms (P<0.05). Seropositive animals in non-case farms were detected by NT in a sero-survey by sampling at slaughterhouses. Therefore, subclinically infected pigs should be considered prior to shipment.

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralCoronavirus InfectionsJapanPorcine epidemic diarrhea virusSwineSwine DiseasesAntibodies, NeutralizingAntibodies, Viralpassive surveillanceporcine epidemic diarrheasubclinical infectionswine

Identifiers

PMID30282841
PMCPMC6261828
OpenAlexW2895454121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.