ArticleThe Journal of cell biology2018
Aneuploidy in intestinal stem cells promotes gut dysplasia in
Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Simple aneuploidy evades p53 surveillance and promotes niche factor-independent growth in human intestinal organoids.Molecular biology of the cell · 2024Article
- Intestine-derived α-synuclein initiates and aggravates pathogenesis of Parkinson's disease in Drosophila.Translational neurodegeneration · 2022Article
- The good, the bad, and the ugly: Evolutionary and pathological aspects of gene dosage alterations.PLoS genetics · 2021Review
- Aneuploidy facilitates dysplastic and tumorigenic phenotypes in the Drosophila gut.Biology open · 2021Article
- Balancing DNA repair to prevent ageing and cancer.Experimental cell research · 2021Review
- Review
- Genomic instability and cancer: lessons fromOpen biology · 2020Review
- Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation.The Journal of cell biology · 2020Article
- Cohesin controls intestinal stem cell identity by maintaining association of Escargot with target promoters.eLife · 2020Article
- Co-Operation between Aneuploidy and Metabolic Changes in Driving Tumorigenesis.International journal of molecular sciences · 2019Review
- Tissue stem cells: the new actors in the aneuploidy field.Cell cycle (Georgetown, Tex.) · 2019Article
- Induced aneuploidy in neural stem cells triggers a delayed stress response and impairs adult life span in flies.PLoS biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aneuploidy is associated with different human diseases including cancer. However, different cell types appear to respond differently to aneuploidy, either by promoting tumorigenesis or causing cell death. We set out to study the behavior of adult
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.