Evidence map›Paper›PMID 30282777›Full record

ArticleMolecular pharmacology2018

Activated CaMKII

Christian R Marks, Brian C Shonesy, Xiaohan Wang, Jason R Stephenson, Colleen M Niswender, Roger J Colbran

Open access · bronzeAbstract read
In one paragraph

Article in Molecular pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christian R MarksDepartments of Molecular Physiology and Biophysics (C.R.M., B.C.S., J.R.S., R.J.C.) and Pharmacology (C.M.N.), Vanderbilt Brain Institute (X.W., R.J.C.), Vanderbilt Kennedy Center for Research on Human Development (C.M.N., R.J.C.), and Vanderbilt Center for Neuroscience Drug Discovery (C.M.N.), Vanderbilt University School of Medicine, Nashville, Tennessee.
Brian C ShonesyDepartments of Molecular Physiology and Biophysics (C.R.M., B.C.S., J.R.S., R.J.C.) and Pharmacology (C.M.N.), Vanderbilt Brain Institute (X.W., R.J.C.), Vanderbilt Kennedy Center for Research on Human Development (C.M.N., R.J.C.), and Vanderbilt Center for Neuroscience Drug Discovery (C.M.N.), Vanderbilt University School of Medicine, Nashville, Tennessee.
Xiaohan WangDepartments of Molecular Physiology and Biophysics (C.R.M., B.C.S., J.R.S., R.J.C.) and Pharmacology (C.M.N.), Vanderbilt Brain Institute (X.W., R.J.C.), Vanderbilt Kennedy Center for Research on Human Development (C.M.N., R.J.C.), and Vanderbilt Center for Neuroscience Drug Discovery (C.M.N.), Vanderbilt University School of Medicine, Nashville, Tennessee.
Jason R StephensonDepartments of Molecular Physiology and Biophysics (C.R.M., B.C.S., J.R.S., R.J.C.) and Pharmacology (C.M.N.), Vanderbilt Brain Institute (X.W., R.J.C.), Vanderbilt Kennedy Center for Research on Human Development (C.M.N., R.J.C.), and Vanderbilt Center for Neuroscience Drug Discovery (C.M.N.), Vanderbilt University School of Medicine, Nashville, Tennessee.
Colleen M NiswenderDepartments of Molecular Physiology and Biophysics (C.R.M., B.C.S., J.R.S., R.J.C.) and Pharmacology (C.M.N.), Vanderbilt Brain Institute (X.W., R.J.C.), Vanderbilt Kennedy Center for Research on Human Development (C.M.N., R.J.C.), and Vanderbilt Center for Neuroscience Drug Discovery (C.M.N.), Vanderbilt University School of Medicine, Nashville, Tennessee.
Roger J ColbranDepartments of Molecular Physiology and Biophysics (C.R.M., B.C.S., J.R.S., R.J.C.) and Pharmacology (C.M.N.), Vanderbilt Brain Institute (X.W., R.J.C.), Vanderbilt Kennedy Center for Research on Human Development (C.M.N., R.J.C.), and Vanderbilt Center for Neuroscience Drug Discovery (C.M.N.), Vanderbilt University School of Medicine, Nashville, Tennessee roger.colbran@vanderbilt.edu.
Vanderbilt University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
MULTIDISCIPLINARY TRAINING IN MOLECULAR ENDOCRINOLOGYT32DK007563 · NIDDK · VANDERBILT UNIVERSITY · PI Richard M O'Brien · 1988 to 2026
$15.9M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Program in NeurogenomicsT32MH065215 · NIMH · VANDERBILT UNIVERSITY · PI ROGER J COLBRAN · 2002 to 2026
$6.4M
Mechanisms of CaM Kinase II Signal TransductionR01MH063232 · NIMH · VANDERBILT UNIVERSITY · PI COLBRAN, ROGER J · 2001 to 2015
$5.4M
CaMKII, endocannabinoids, synaptic plasticity and motor functionR01NS078291 · NINDS · VANDERBILT UNIVERSITY · PI COLBRAN, ROGER J · 2012 to 2016
$1.8M
Endocannabinoids in social and repetitive behavioral domainsK01MH107765 · NIMH · VANDERBILT UNIVERSITY · PI SHONESY, BRIAN C · 2015 to 2018
$454k
Reciprocal mGluR5-CaMKII regulationF31MH109196 · NIMH · VANDERBILT UNIVERSITY · PI MARKS, CHRISTIAN R. · 2015 to 2017
$56k
NCI NIH HHS P30 CA068485NICHD NIH HHS U54 HD083211NIDDK NIH HHS P30 DK020593NIDDK NIH HHS T32 DK007563NIMH NIH HHS F31 MH109196NIMH NIH HHS K01 MH107765NIMH NIH HHS R01 MH063232NIMH NIH HHS T32 MH065215NINDS NIH HHS R01 NS078291
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CalmodulinCell LineCell MembraneFemaleHEK293 CellsHumansImmunoprecipitationMaleMiceMice, KnockoutProtein BindingReceptor, Metabotropic Glutamate 5Signal TransductionCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CalmodulinReceptor, Metabotropic Glutamate 5

Identifiers

PMID30282777
PMCPMC6207916
OpenAlexW2894941693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.