Evidence map›Paper›PMID 30282770›Full record

ArticleNeurology2018

Racial differences in recurrent ischemic stroke risk and recurrent stroke case fatality.

Karen C Albright, Lei Huang, Justin Blackburn, George Howard, Michael Mullen, Vera Bittner, Paul Muntner, Virginia Howard

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05907629 (Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging), which is not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05907629 recruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging

TypeobservationalSponsorYale UniversityRan2024 to 2029Enrolled300ConditionsStroke, Intracranial Atherosclerotic Stenosis (ICAS)ArmsMRI
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Repeated mechanical thrombectomy for recurrent large vessel occlusion: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Karen C AlbrightFrom the Departments of Epidemiology (K.C.A., L.H., P.M., V.H.), Health Care Organization and Policy (J.B.), Biostatistics (G.H.), and Medicine (V.B.), University of Alabama at Birmingham; Geriatric Research, Education and Clinical Center (K.C.A.), Birmingham VA Medical Center, AL; and Department of Neurology (M.M.), University of Pennsylvania, Philadelphia. albrighk@upstate.edu.
Lei HuangFrom the Departments of Epidemiology (K.C.A., L.H., P.M., V.H.), Health Care Organization and Policy (J.B.), Biostatistics (G.H.), and Medicine (V.B.), University of Alabama at Birmingham; Geriatric Research, Education and Clinical Center (K.C.A.), Birmingham VA Medical Center, AL; and Department of Neurology (M.M.), University of Pennsylvania, Philadelphia.
Justin BlackburnFrom the Departments of Epidemiology (K.C.A., L.H., P.M., V.H.), Health Care Organization and Policy (J.B.), Biostatistics (G.H.), and Medicine (V.B.), University of Alabama at Birmingham; Geriatric Research, Education and Clinical Center (K.C.A.), Birmingham VA Medical Center, AL; and Department of Neurology (M.M.), University of Pennsylvania, Philadelphia.
George HowardFrom the Departments of Epidemiology (K.C.A., L.H., P.M., V.H.), Health Care Organization and Policy (J.B.), Biostatistics (G.H.), and Medicine (V.B.), University of Alabama at Birmingham; Geriatric Research, Education and Clinical Center (K.C.A.), Birmingham VA Medical Center, AL; and Department of Neurology (M.M.), University of Pennsylvania, Philadelphia.
Michael MullenFrom the Departments of Epidemiology (K.C.A., L.H., P.M., V.H.), Health Care Organization and Policy (J.B.), Biostatistics (G.H.), and Medicine (V.B.), University of Alabama at Birmingham; Geriatric Research, Education and Clinical Center (K.C.A.), Birmingham VA Medical Center, AL; and Department of Neurology (M.M.), University of Pennsylvania, Philadelphia.
Vera BittnerFrom the Departments of Epidemiology (K.C.A., L.H., P.M., V.H.), Health Care Organization and Policy (J.B.), Biostatistics (G.H.), and Medicine (V.B.), University of Alabama at Birmingham; Geriatric Research, Education and Clinical Center (K.C.A.), Birmingham VA Medical Center, AL; and Department of Neurology (M.M.), University of Pennsylvania, Philadelphia.
Paul MuntnerFrom the Departments of Epidemiology (K.C.A., L.H., P.M., V.H.), Health Care Organization and Policy (J.B.), Biostatistics (G.H.), and Medicine (V.B.), University of Alabama at Birmingham; Geriatric Research, Education and Clinical Center (K.C.A.), Birmingham VA Medical Center, AL; and Department of Neurology (M.M.), University of Pennsylvania, Philadelphia.
Virginia HowardFrom the Departments of Epidemiology (K.C.A., L.H., P.M., V.H.), Health Care Organization and Policy (J.B.), Biostatistics (G.H.), and Medicine (V.B.), University of Alabama at Birmingham; Geriatric Research, Education and Clinical Center (K.C.A.), Birmingham VA Medical Center, AL; and Department of Neurology (M.M.), University of Pennsylvania, Philadelphia.
Birmingham VA Medical Center · USGeriatric Research Education and Clinical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine black-white differences in 1-year recurrent stroke and 30-day case fatality after a recurrent stroke in older US adults.

methodsWe conducted a retrospective cohort study using a 5% random sample of Medicare beneficiaries with fee-for-service health insurance coverage who were hospitalized for ischemic stroke between 1999 and 2013. Hazard ratios for recurrent ischemic stroke and risk ratios for 30-day case fatality comparing blacks to whites were calculated with adjustment for demographics, risk factors, and competing risk of death when appropriate.

resultsAmong 128,789 Medicare beneficiaries having an ischemic stroke (mean age 80 years [SD 8 years], 60.4% male), 11.1% were black. The incidence rate of recurrent ischemic stroke per 1,000 person-years for whites and blacks was 108 (95% confidence interval [CI], 106-111) and 154 (95% CI 147-162) , respectively. The multivariable-adjusted hazard ratio for recurrent stroke among blacks compared with whites was 1.36 (95% CI 1.29-1.44). The case fatality after recurrent stroke for blacks and whites was 21% (95% CI 21%-22%) and 16% (95% CI 15%-18%), respectively. The multivariable-adjusted relative risk for mortality within 30 days of a recurrent stroke among blacks compared with whites was 0.82 (95% CI 0.73-0.93).

conclusionThe risk of stroke recurrence among older Americans hospitalized for ischemic stroke is higher for blacks compared to whites, while 30-day case fatality after recurrent stroke remains lower for blacks.

Indexed as

AgedAged, 80 and overBlack or African AmericanCohort StudiesFemaleHumansIncidenceMaleMedicareRecurrenceRetrospective StudiesStrokeUnited StatesWhite People

Identifiers

PMID30282770
PMCPMC6251602
OpenAlexW2894729445

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.