Evidence map›Paper›PMID 30282769›Full record

ArticleNeurology2018

Sleep duration and risk of incident stroke by age, sex, and race: The REGARDS study.

Megan E Petrov, George Howard, Michael A Grandner, Dawn Kleindorfer, Jennifer R Molano, Virginia J Howard

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Sleep Quality Reports From Family Caregivers and Matched Non-caregiving Controls in a Population-Based Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Megan E PetrovFrom the College of Nursing & Health Innovation (M.E.P.), Arizona State University, Phoenix; Departments of Biostatistics (G.H.) and Epidemiology (V.J.H.), University of Alabama at Birmingham; Department of Psychiatry (M.A.G.), University of Arizona, Tucson; and Department of Neurology & Rehabilitation Medicine (D.K., J.R.M.), University of Cincinnati, OH. Megan.Petrov@asu.edu.
George HowardFrom the College of Nursing & Health Innovation (M.E.P.), Arizona State University, Phoenix; Departments of Biostatistics (G.H.) and Epidemiology (V.J.H.), University of Alabama at Birmingham; Department of Psychiatry (M.A.G.), University of Arizona, Tucson; and Department of Neurology & Rehabilitation Medicine (D.K., J.R.M.), University of Cincinnati, OH.
Michael A GrandnerFrom the College of Nursing & Health Innovation (M.E.P.), Arizona State University, Phoenix; Departments of Biostatistics (G.H.) and Epidemiology (V.J.H.), University of Alabama at Birmingham; Department of Psychiatry (M.A.G.), University of Arizona, Tucson; and Department of Neurology & Rehabilitation Medicine (D.K., J.R.M.), University of Cincinnati, OH.
Dawn KleindorferFrom the College of Nursing & Health Innovation (M.E.P.), Arizona State University, Phoenix; Departments of Biostatistics (G.H.) and Epidemiology (V.J.H.), University of Alabama at Birmingham; Department of Psychiatry (M.A.G.), University of Arizona, Tucson; and Department of Neurology & Rehabilitation Medicine (D.K., J.R.M.), University of Cincinnati, OH.
Jennifer R MolanoFrom the College of Nursing & Health Innovation (M.E.P.), Arizona State University, Phoenix; Departments of Biostatistics (G.H.) and Epidemiology (V.J.H.), University of Alabama at Birmingham; Department of Psychiatry (M.A.G.), University of Arizona, Tucson; and Department of Neurology & Rehabilitation Medicine (D.K., J.R.M.), University of Cincinnati, OH.
Virginia J HowardFrom the College of Nursing & Health Innovation (M.E.P.), Arizona State University, Phoenix; Departments of Biostatistics (G.H.) and Epidemiology (V.J.H.), University of Alabama at Birmingham; Department of Psychiatry (M.A.G.), University of Arizona, Tucson; and Department of Neurology & Rehabilitation Medicine (D.K., J.R.M.), University of Cincinnati, OH.

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

objectiveTo investigate the association between reported sleep duration and incident stroke in a US cohort of black and white adults, and evaluate race, age, and sex as potential effect modifiers.

methodsFrom 2008 to 2010, 16,733 black and white adults, aged ≥45 years, without a history of stroke or sleep-disordered breathing from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, reported their habitual sleep duration (<6, 6.0-6.9, 7.0-8.9 [reference], ≥9 hours). Incident strokes were identified through biannual participant contact followed by physician adjudication of medical records. Cox proportional hazards analysis was conducted to calculate hazard ratios of interactions between sleep duration with race, age, sex, and 2-way combinations of these factors on incident stroke adjusting for stroke risk factors and sleep-disordered breathing risk.

resultsThe sample comprised 10.4% (n = 1,747) short sleepers (<6 hours) and 6.8% (n = 1,134) long sleepers (≥9 hours). Over an average 6.1 years follow-up, 460 strokes occurred. There were significant interactions between sleep duration and race (

conclusionsThe association of sleep duration with incident stroke differs by race and sex, with short sleep duration among black men associated with decreased risk, whereas long sleep duration among white men associated with increased risk for stroke.

Indexed as

SleepAge FactorsCohort StudiesFemaleHumansIncidenceMaleMiddle AgedRace FactorsSex FactorsStrokeTime Factors

Identifiers

PMID30282769
PMCPMC6207412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.