Evidence map›Paper›PMID 30282530›Full record

ArticleToxicologic pathology2018

Proceedings of the 2018 National Toxicology Program Satellite Symposium.

Susan A Elmore, Vinicius Carreira, Caralyn S Labriola, Debabrata Mahapatra, Sean R McKeag, Matthias Rinke, Cynthia Shackelford, Bhanu Singh, Ashley Talley, Shannon M Wallace and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Toxicologic pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Selective inhibition of integrin αvβ6 leads to rapid induction of urinary bladder tumors in cynomolgus macaques.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Susan A Elmore1 Cellular and Molecular Pathology Branch, National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.ORCID 0000-0002-1680-9176
Vinicius Carreira2 Janssen Research & Development, La Jolla, California, USA.
Caralyn S Labriola3 Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Debabrata Mahapatra4 Integrated Laboratory Systems, Inc., Research Triangle Park, North Carolina, USA.
Sean R McKeag5 Covance Laboratories, Harrogate, North Yorkshire, United Kingdom.
Matthias Rinke6 (retired), Bayer AG, Wuppertal, Germany.
Cynthia Shackelford7 Experimental Pathology Laboratories, Inc., Research Triangle Park, North Carolina, USA.
Bhanu Singh8 Janssen Research & Development, Spring House, Pennsylvania, USA.
Ashley Talley9 Charles River Laboratories, Inc., Durham, North Carolina, USA.
Shannon M Wallace10 Experimental Pathology Laboratories, Inc., Sterling, Virginia, USA.
Lyn M Wancket11 NAMSA, Northwood, Ohio, USA.
Cynthia J Willson4 Integrated Laboratory Systems, Inc., Research Triangle Park, North Carolina, USA.
Experimental Pathology Laboratories · USJanssen (United States) · USTriangle · USBayer (Germany) · DECharles River Laboratories (United States) · USCovance (United Kingdom) · GBNational Institutes of Health · USNorthwood University · USWake Forest University · US

Funding

Intramural NIH HHS Z99 ES999999
6 · The paper itself

Abstract

The 2018 annual National Toxicology Program Satellite Symposium, entitled "Pathology Potpourri," was held in Indianapolis, Indiana, at the Society of Toxicologic Pathology's 37th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers' talks along with select images that were used by the audience for voting and discussion. Various lesions and other topics covered during the symposium included seminiferous tubule dysgenesis in rats, ameloblast and odontoblast degeneration/necrosis in a Sprague Dawley rat, intestinal leiomyositis in a beagle dog, gallbladder mucinous hyperplasia, focus of hepatocellular alteration and bile duct alteration in otters, renal tubule cytoplasmic vacuolation with basophilic granules in mice treated swith antisense oligonucleotide therapy, a uterine choriocarcinoma in a rhesus macaque, and rete ovarii proliferative ovarian lesions in various aged rat strains. One particularly provocative lesion was a malignant neoplastic proliferation in the renal pelvic region of a cynomolgus macaque from a 21-day study. Additional challenging lesions included thyroid proliferative lesions in zebra fish and gross findings in fish larvae during routine chemical screening. The Rabbit and Minipig International Harmonization of Nomenclature and Diagnostic Criteria Organ Working Groups also presented a series of challenging lesions.

Indexed as

ToxicologyAnimalsCongresses as Topicameloblast degenerationfish larvae gross lesionsgallbladder mucinous hyperplasiaINHANDintestinal leiomyositisNTP Satellite Symposiumrenal neoplasiarenal tubule basophilic granulesrete ovarii hyperplasiatestis dysgenesisuterine choriocarcinoma

Identifiers

PMID30282530
PMCPMC6298844
OpenAlexW2916969653

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.