Evidence map›Paper›PMID 30282468›Full record

ArticleThe Annals of pharmacotherapy2019

Race-Specific Patterns of Treatment Intensification Among Hypertensive Patients Using Home Blood Pressure Monitoring: Analysis Using Defined Daily Doses in the Heart Healthy Lenoir Study.

Doyle M Cummings, Alyssa Adams, Jacquie Halladay, Alan Hinderliter, Katrina E Donahue, Crystal W Cene, Quefeng Li, Cassandra Miller, Beverly Garcia, Jim Tillman and 2 more

Open access · greenAbstract read
In one paragraph

Article in The Annals of pharmacotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Doyle M Cummings1 East Carolina University, Greenville, NC, USA.
Alyssa Adams1 East Carolina University, Greenville, NC, USA.
Jacquie Halladay2 University of North Carolina-Chapel Hill, NC, USA.
Alan Hinderliter2 University of North Carolina-Chapel Hill, NC, USA.
Katrina E Donahue2 University of North Carolina-Chapel Hill, NC, USA.ORCID 0000-0003-4075-2875
Crystal W Cene2 University of North Carolina-Chapel Hill, NC, USA.
Quefeng Li2 University of North Carolina-Chapel Hill, NC, USA.
Cassandra Miller2 University of North Carolina-Chapel Hill, NC, USA.
Beverly Garcia2 University of North Carolina-Chapel Hill, NC, USA.
Jim Tillman3 Open Water Consulting, Cape Carteret, NC, USA.
Edwin Little4 Kinston Medical Specialists, Pink Hill, NC, USA.
Darren DeWalt2 University of North Carolina-Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USEast Carolina University · USKinston Medical Specialists · US

Funding

REDUCING DISPARITIES IN HYPERTENSION WITH A PRACTICE-BASED ENHANCED CARE PROGRAMP50HL105184 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AMMERMAN, ALICE S · 2010 to 2014
$10.1M
NHLBI NIH HHS P50 HL105184
6 · The paper itself

Abstract

backgroundRacial disparities in blood pressure (BP) control persist, but whether differences by race in antihypertensive medication intensification (AMI) contribute is unknown.

objectiveTo compare AMI by race for patients with elevated home BP readings.

methodsThis prospective cohort study followed adult patients from 6 rural primary care practices who used home BP monitoring (HBPM) and recorded/reported values. For providers, AMI was encouraged when mean HBPM systolic blood pressure (SBP) values were ⩾135 mm Hg; patients received phone-based coaching on HBPM technique and sharing HBPM findings. AMI was assessed between baseline and 12 months using defined daily dose (DDD) and summed to create a total antihypertensive DDD value.

resultsA total of 217 patients (mean age = 61.4 ± 10.2 years; 66% female; 57% black) provided usable HBPM data. Among 90 (41%) intensification-eligible hypertensive patients (ie, mean HBPM SBP values for 6-months ⩾135 mm Hg), mean total antihypertensive DDD was increased in 61% at 12 months. Blacks had significantly higher mean DDD at baseline and 12 months, but intensification (+0.72 vs +0.65; P = 0.83) was similar by race. However, intensification was greater in males than females (+1.1 vs +0.39; P = 0.031). Reduction in mean SBP following intensification was greater in white versus black patients (-8.2 vs -3.9 mm Hg; P = 0.14). Conclusion/Relevance: Treatment intensification in HBPM users was similar by race, differed significantly by gender, and may produce a greater response in white patients. Differential AMI in HBPM users does not appear to contribute to persistent racial disparities in BP control.

Indexed as

Black or African AmericanAdultAgedAlgorithmsAntihypertensive AgentsBlood PressureBlood Pressure Monitoring, AmbulatoryContraindicationsFemaleHumansHypertensionMaleMiddle AgedProspective StudiesRace FactorsSex FactorsAntihypertensive Agentshypertension controlracial disparitiestreatment intensification

Identifiers

PMID30282468
PMCPMC7433691
OpenAlexW2894907697

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.