Evidence map›Paper›PMID 30282113›Full record

Observational studyTropical medicine & international health : TM & IH2018

Linkage to care and antiretroviral therapy initiation by testing modality among individuals newly diagnosed with HIV in Tanzania, 2014-2017.

Christopher T Rentsch, Alison Wringe, Richard Machemba, Denna Michael, Mark Urassa, Jim Todd, Georges Reniers, Basia Zaba

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Tropical medicine & international health : TM & IH, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Christopher T RentschDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Alison WringeDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Richard MachembaThe Tazama Project, National Institute for Medical Research, Mwanza, Tanzania.
Denna MichaelThe Tazama Project, National Institute for Medical Research, Mwanza, Tanzania.
Mark UrassaThe Tazama Project, National Institute for Medical Research, Mwanza, Tanzania.
Jim ToddDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Georges ReniersDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Basia ZabaDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK.
National Institute for Medical Research · TZLondon School of Hygiene & Tropical Medicine · GBAgincourt Health and Socio-Demographic Surveillance System · ZA

Funding

Medical Research Council MR/P014313/1
6 · The paper itself

Abstract

objectiveTo measure linkage to care and antiretroviral therapy (ART) initiation among newly diagnosed individuals with HIV in a rural Tanzanian community.

methodsWe included all new HIV diagnoses of adults made between 2014 and 2017 during community- or facility-based HIV testing and counselling (HTC) in a rural ward in northwest Tanzania. Community-based HTC included population-level HIV serological testing (sero-survey), and facility-based HTC included a stationary, voluntary HTC clinic (VCT) and an antenatal clinic (ANC) offering provider-initiated HTC (ANC-PITC). Cox regression models were used to compare linkage to care rates by testing modality and identify associated factors. Among those in care, we compared initial CD4 cell counts and ART initiation rates by testing modality.

resultsA total of 411 adults were newly diagnosed, of whom 10% (27/265 sero-survey), 18% (3/14 facility-based ANC-PITC) and 53% (68/129 facility-based VCT) linked to care within 90 days. Individuals diagnosed using facility-based VCT were seven times (95% CI: 4.5-11.0) more likely to link to care than those diagnosed in the sero-survey. We found no difference in linkage rates between those diagnosed using facility-based ANC-PITC and sero-survey (P = 0.26). Among individuals in care, 63% of those in the sero-survey had an initial CD4 count >350 cells/mm

conclusionsCommunity-based sero-surveys are important for earlier diagnosis of HIV-positive individuals; however, interventions are essential to facilitate linkage to care.

Indexed as

AdolescentAdultAnti-Retroviral AgentsCohort StudiesCommunity Health ServicesFemaleHIV InfectionsHumansMaleMiddle AgedPatient Acceptance of Health CareRural PopulationTanzaniaTimeYoung AdultAnti-Retroviral AgentsAfrique subsaharienneétudes longitudinalesHIVHIV testinglien vers les soinslinkage to carelongitudinal studiespopulation surveillancesub-Saharan Africasurveillance de la populationtest du VIHVIH

Identifiers

PMID30282113
PMCPMC6334504
OpenAlexW2894723055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.