Evidence map›Paper›PMID 30281908›Full record

ArticleJournal of biomedical materials research. Part B, Applied biomaterials2019

Preparation of photothermal palmitic acid/cholesterol liposomes.

Chase S Linsley, Max Zhu, Viola Y Quach, Benjamin M Wu

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. In Vivo Evaluation of PamJournal of peptide science : an official publication of the European Peptide Society · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chase S LinsleyDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, California 90095, USA.ORCID 0000-0002-8259-5487
Max ZhuDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, California 90095, USA.
Viola Y QuachDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, California 90095, USA.
Benjamin M WuDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, California 90095, USA.
University of California, Los Angeles · US

Funding

HIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6M
Growth factor delivery using light-sensitive fibrin to treat chronic woundsR21AR064437 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TAWIL, BILL, WU, BENJAMIN M · 2014 to 2015
$359k
Electron Imaging Center for NanoMachines, NIH 1S10RR23057National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health (NIH) R21AR064437NCRR NIH HHS S10 RR023057NIAMS NIH HHS R21 AR064437UCLA Broad Stem Cell Research Center, Stem Cell Research Award
6 · The paper itself

Abstract

Indocyanine green (ICG) is the only FDA-approved near-infrared dye and it is currently used clinically for diagnostic applications. However, there is significant interest in using ICG for triggered drug delivery applications and heat ablation therapy. Unfortunately, free ICG has a short half-life in vivo and is rapidly cleared from circulation. Liposomes have been frequently used to improve ICG's stability and overall time of effectiveness in vivo, but they have limited stability due to the susceptibility of phospholipids to hydrolysis and oxidation. In this study, nonphospholipid liposomes were used to encapsulate ICG, and the resulting liposomes were characterized for size, encapsulation efficiency, stability, and photothermal response. Using the thin-film hydration method, an ICG encapsulation efficiency of 54% was achieved, and the liposomes were stable for up to 12 weeks, with detectable levels of encapsulated ICG up to week 4. Additionally, ICG-loaded liposomes were capable of rapidly producing a significant photothermal response upon exposure to near-infrared light, and this photothermal response was able to induce changes in the mechanical properties of thermally responsive hydrogels. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B: 1384-1392, 2019.

Indexed as

Hyperthermia, InducedPhototherapyCholesterolIndocyanine GreenLiposomesPalmitic AcidCholesterolIndocyanine GreenLiposomesPalmitic Acidcardiogreenchromophoreindocyanine greenliposomenanotechnologyphotothermal effect

Identifiers

PMID30281908
PMCPMC9297699
OpenAlexW2895418580

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.