ArticleAmerican journal of primatology2019
One-year change in cognitive flexibility and fine motor function in middle-aged male and female marmosets (Callithrix jacchus).
Article in American journal of primatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
- Home-cage pharmacology in marmosets: behavioral effects of scopolamine.Psychopharmacology · 2026Article
- Changes in microglial morphologies during brain aging in common marmosets.Brain structure & function · 2026Article
- Scopolamine induced learning deficit in marmosets.Research square · 2025Article
- Inhibitory control tests in non-human animals: validity, reliability, and perspectives.Biological reviews of the Cambridge Philosophical Society · 2025Review
- Scopolamine induced learning deficit in marmosets.bioRxiv : the preprint server for biology · 2025Article
- Distinct roles of two thalamostriatal systems in visually triggered decision-making in common marmosets.iScience · 2025Article
- Article
- How Do Common Marmosets Maintain the Balance Between Response Execution and Action Inhibition?American journal of primatology · 2025Article
- Alcohol, flexible behavior, and the prefrontal cortex: Functional changes underlying impaired cognitive flexibility.Neuropharmacology · 2024Review
- Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Cognitive development from infancy to young adulthood in common marmosets (Callithrix jacchus): Effect of age, sex, and hormones on learning and affective state.Developmental psychobiology · 2023Article
- Domain-Specific Cognitive Impairment Reflects Prefrontal Dysfunction in Aged Common Marmosets.eNeuro · 2023Article
- Age differences in cortical thickness and their association with cognition in chimpanzee (Pan troglodytes).Neurobiology of aging · 2023Article
- Domain-specific cognitive impairment reflects prefrontal dysfunction in aged common marmosets.bioRxiv : the preprint server for biology · 2023Article
- Structural and functional variations in the prefrontal cortex are associated with learning in pre-adolescent common marmosets (Callithrix jacchus).Behavioural brain research · 2022Article
- Social ageing: exploring the drivers of late-life changes in social behaviour in mammals.Biology letters · 2022Review
- Early Alzheimer's disease-like reductions in gray matter and cognitive function with aging in nonhuman primates.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- Sex differences in cognitive aging: a 4-year longitudinal study in marmosets.Neurobiology of aging · 2022Article
- Age- and cognition-related differences in the gray matter volume of the chimpanzee brain (Pan troglodytes): A voxel-based morphometry and conjunction analysis.American journal of primatology · 2021Article
- Age-related changes in chimpanzee (Pan troglodytes) cognition: Cross-sectional and longitudinal analyses.American journal of primatology · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The common marmoset (Callithrix jacchus) is uniquely suited for longitudinal studies of cognitive aging, due to a relatively short lifespan, sophisticated cognitive abilities, and patterns of brain aging that resemble those of humans. We examined cognitive function and fine motor skills in male and female marmosets (mean age ∼5 at study entry) followed longitudinally for 2 years. Each year, monkeys were tested on a reversal learning task with three pairs of stimuli (n = 18, 9 females) and a fine motor task requiring them to grasp small rewards from two staircases (Hill and Valley test, n = 12, 6 females). There was little evidence for a decline in cognitive flexibility between the two time points, in part because of practice effects. However, independent of year of testing, females took longer than males to reach criterion in the reversals, indicating impaired cognitive flexibility. Motivation was unlikely to contribute to this effect, as males refused a greater percentage of trials than females in the reversals. With regards to motor function, females were significantly faster than males in the Hill and Valley task. From Year 1 to Year 2, a slight slowing of motor function was observed in both sexes, but accuracy decreased significantly in males only. This study (1) demonstrates that marmosets exhibit sex differences in cognitive flexibility and fine motor function that resemble those described in humans; (2) that changes in fine motor function can already be detected at middle-age; and (3) that males may experience greater age-related changes in fine motor skills than females. Additional data points will determine whether these sex and age differences persist over time.
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