Evidence map›Paper›PMID 30281688›Full record

Observational studyArquivos brasileiros de cardiologia2018

Prognostic Differences between Men and Women with Acute Coronary Syndrome. Data from a Brazilian Registry.

Alexandre de Matos Soeiro, Pedro Gabriel Melo de Barros E Silva, Eduardo Alberto de Castro Roque, Aline Siqueira Bossa, Bruno Biselli, Tatiana de Carvalho Andreucci Torres Leal, Maria Carolina Feres de Almeida Soeiro, Fábio Grunspun Pitta, Carlos V Serrano, Múcio Tavares Oliveira

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Arquivos brasileiros de cardiologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Cardiovascular Statistics - Brazil 2023.Arquivos brasileiros de cardiologia · 2024
    Article
  4. Article
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Article
  10. Sex Differences in Acute Coronary Syndromes: A Global Perspective.Journal of cardiovascular development and disease · 2022
    Review
  11. Cardiovascular Statistics - Brazil 2021.Arquivos brasileiros de cardiologia · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cardiovascular Statistics - Brazil 2020.Arquivos brasileiros de cardiologia · 2020
    Article
  17. Article
  18. Subclinical thyroid diseases as a non-classical risk factor for cardiovascular diseases.Sao Paulo medical journal = Revista paulista de medicina · 2020
    Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Alexandre de Matos SoeiroUnidade Clínica de Emergência - InCor - HCFMUSP, São Paulo, SP - Brazil.
Pedro Gabriel Melo de Barros E SilvaHospital TotalCor, São Paulo, SP - Brazil.
Eduardo Alberto de Castro RoqueHospital Metropolitano, Serra, ES - Brazil.
Aline Siqueira BossaUnidade Clínica de Emergência - InCor - HCFMUSP, São Paulo, SP - Brazil.
Bruno BiselliUnidade Clínica de Emergência - InCor - HCFMUSP, São Paulo, SP - Brazil.
Tatiana de Carvalho Andreucci Torres LealUnidade Clínica de Emergência - InCor - HCFMUSP, São Paulo, SP - Brazil.
Maria Carolina Feres de Almeida SoeiroUnidade Clínica de Emergência - InCor - HCFMUSP, São Paulo, SP - Brazil.
Fábio Grunspun PittaUnidade Clínica de Emergência - InCor - HCFMUSP, São Paulo, SP - Brazil.
Carlos V SerranoUnidade Clínica de Emergência - InCor - HCFMUSP, São Paulo, SP - Brazil.
Múcio Tavares OliveiraUnidade Clínica de Emergência - InCor - HCFMUSP, São Paulo, SP - Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGender-related differences have been reported in patients with acute coronary syndrome. The description of this comparative finding in a Brazilian registry has not yet been documented.

objectiveTo compare male vs. female patients regarding the baseline characteristics, coronary findings, treatment and in-hospital and long-term prognosis.

methodsThis is a retrospective, multicenter and observational study that included 3,745 patients (2,437 males and 1,308 females) between May 2010 and May 2015. The primary in-hospital outcome was all-cause mortality. The secondary outcome consisted of combined events (cardiogenic shock, reinfarction, death, stroke and bleeding). The comparison between groups was performed using the chi-square and the t test, considering p < 0.05 as significant. In the long term, mortality and combined events were assessed using the Kaplan-Meier method, with a mean follow-up of 8.79 months.

resultsThe mean age was 60.3 years for males and 64.6 for females (p < 0.0001). The most prevalent risk factor was systemic arterial hypertension in 72.9% of the women and 67.8% of the men (p = 0.001). Percutaneous coronary intervention was carried out in 44.9% of the males and 35.4% of the females (p < 0.0001), and coronary artery bypass grafting (CABG) was performed in 17% of the males and 11.8% of females (p < 0.0001), with a higher prevalence of three-vessel coronary artery disease in males (27.3% vs. 16.2%, p < 0.0001). Approximately 79.9% of the female patients received a diagnosis of acute coronary syndrome without ST-segment elevation, while in the male patients, this diagnosis was attained in 71.5% (p < 0.0001). No significant differences were observed between the groups in the short and long term, regarding both mortality and the combined events.

conclusionSeveral gender-related differences were observed in patients with acute coronary syndrome regarding the demographic characteristics, coronary artery disease pattern and implemented treatment. However, the prognostic evolution was similar between the groups.

Indexed as

Acute Coronary SyndromeAgedAge FactorsBrazilComorbidityFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedPercutaneous Coronary InterventionPrognosisRegistriesRetrospective StudiesSex Distribution

Identifiers

PMID30281688
PMCPMC6248255

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.