Evidence map›Paper›PMID 30281596›Full record

ArticlePloS one2018

Preservative effect of Chinese cabbage (Brassica rapa subsp. pekinensis) extract on their molecular docking, antioxidant and antimicrobial properties.

Momna Rubab, Ramachandran Chellia, Kandasamy Saravanakumar, Suresh Mandava, Imran Khan, Charles Nkufi Tango, Mohammad Shakhawat Hussain, Eric Banan-Mwine Daliri, Se-Hun Kim, Sudha Rani Ramakrishnan and 5 more

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Metabolite Profiling and Antimicrobial Activities ofMolecules (Basel, Switzerland) · 2025
    Article
  3. Antioxidant and antimicrobial potential of two extracts fromSaudi journal of biological sciences · 2022
    Article
  4. Article
  5. A Review on Phytochemicals of the GenusMolecules (Basel, Switzerland) · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Momna RubabDepartment of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon, South Korea.
Ramachandran ChelliaDepartment of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon, South Korea.
Kandasamy SaravanakumarDepartment of Medical Biotechnology, College of Biomedical Sciences, Kangwon National University, Chuncheon, South Korea.ORCID 0000-0002-4465-4378
Suresh MandavaCollege of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Imran KhanDepartment of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon, South Korea.
Charles Nkufi TangoDepartment of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon, South Korea.
Mohammad Shakhawat HussainDepartment of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon, South Korea.
Eric Banan-Mwine DaliriDepartment of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon, South Korea.
Se-Hun KimDepartment of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon, South Korea.
Sudha Rani RamakrishnanSchool of Food Science and Biotechnology, Kyungpook National University, Daegu, South Korea.
Myeong-Hyeon WangDepartment of Medical Biotechnology, College of Biomedical Sciences, Kangwon National University, Chuncheon, South Korea.
Jongkook LeeCollege of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Joong-Ho KwonSchool of Food Science and Biotechnology, Kyungpook National University, Daegu, South Korea.
Sangeeta ChandrashekarSri Venkateshwara Dental College, Thalambur, Chennai, Tamil Nadu, India.
Deog-Hwan OhDepartment of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon, South Korea.ORCID 0000-0002-7472-0436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed at investigating the antimicrobial activity of different solvent extracts of Chinese cabbage Brassica rapa subsp. pekinensis (BRARP) and their antioxidant and cytotoxicity properties. Of the different solvents extracts, the chloroform extracts (CE) were significantly inhibited the bacterial pathogens at minimum inhibitory concentration (MIC) of 16.5 mg.mL-1. Biochemical analysis revealed that total phenol (62.6 ± 0.05 mg GAE.g-1) and flavonoids (27.6 ± 0.04 mg QE.g-1) were higher in the extracts of BRARP, which resulted in enhanced antioxidant activity in CE. A total of eight dominant compounds were detected in the potent antimicrobial extract from BRARP based on GC-MS analysis. The molecular interactions study revealed that, among the screened compounds the 1,2-benzenedicarboxylic acid and 2,3-dicyanopropionamide interacted with the active site of pathogenicity and survival related protein with lipopolysaccharide (LpxC) with higer binding energy. This work concluded that the 1, 2-Benzenedicarboxylic acid and 2, 3-Dicyanopropionamide from BRARP was reported to be good non-cytotoxic and antioxidant antimicrobials against bacterial pathogens.

Indexed as

Anti-Infective AgentsAntioxidantsBacteriaBrassica rapaFlavonoidsMicrobial Sensitivity TestsMolecular Docking SimulationPhenolsPlant ExtractsPreservatives, PharmaceuticalAnti-Infective AgentsAntioxidantsFlavonoidsPhenolsPlant ExtractsPreservatives, Pharmaceutical

Identifiers

PMID30281596
PMCPMC6169867

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.