Evidence map›Paper›PMID 30281430›Full record

ArticleIEEE transactions on bio-medical engineering2019

Lung Ultrasound Surface Wave Elastography for Assessing Interstitial Lung Disease.

Xiaoming Zhang, Boran Zhou, Thomas Osborn, Brian Bartholmai, Sanjay Kalra

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06844331 (ULtrasOund Applicability in the Assessment of Patients With fibRosing Interstitial Lung Disease), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06844331 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

ULtrasOund Applicability in the Assessment of Patients With fibRosing Interstitial Lung Disease (LORD): A Research Protocol of a Single Center, Real-life, Prospective Observational Study

TypeobservationalSponsorOdense University HospitalRan2024 to 2026Enrolled117ConditionsFibrosing Interstitial Lung Diseases, Thoracic UltrasoundArmsThoracic ultrasound
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
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  13. Grading Bleomycin-Induced Pulmonary Fibrosis in ex vivo Mouse Lungs Using Ultrasound Image Analysis.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2021
    Article
  14. Article
  15. Ultrasound Elastography for Lung Disease Assessment.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiaoming Zhang
Boran Zhou
Thomas Osborn
Brian Bartholmai
Sanjay Kalra
Mayo Clinic in Arizona · USWinnMed · US

Funding

Measurement of surface lung tissue using ultrasoundR01HL125234 · NHLBI · MAYO CLINIC ROCHESTER · PI ZHANG, XIAOMING · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL125234
6 · The paper itself

Abstract

objectiveOur goal is to translate lung ultrasound surface wave elastography (LUSWE) for assessing patients with interstitial lung disease (ILD) and various connective tissue diseases including systemic sclerosis (SSc).

methodsLUSWE was used to measure the surface wave speed of lung at 100, 150, and 200 Hz through six intercostal lung spaces for 91 patients with ILD and 30 healthy control subjects. In addition, skin viscoelasticity was measured on both forearms and upper arms for patients and controls.

resultsThe surface wave speeds of patients' lungs were significantly higher than those of control subjects. Patient skin elasticity and viscosity were significantly higher than those of control subjects. In dividing ILD patients into two groups, ILD with SSc patients and ILD without SSc patients, significant differences between each patient group with the control group were found for both the lung and skin. No significant differences were found between the two patient groups, although there were some differences at a few locations and at 100 Hz for skin viscoelasticity.

conclusionSignificant differences of surface wave speed were found between ILD patients and healthy control subjects for both the lung and skin. SIGNIFICANCE: LUSWE may be useful for assessing ILD and SSc and screening early stage patients.

Indexed as

AdultAgedAged, 80 and overElasticity Imaging TechniquesFemaleHumansImage Interpretation, Computer-AssistedLungLung Diseases, InterstitialMaleMiddle AgedViscosityYoung Adult

Identifiers

PMID30281430
PMCPMC6541007
OpenAlexW2963297339

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.