Evidence map›Paper›PMID 30281378›Full record

Trial reportJournal of global oncology2018

Axillary Lymph Node Dissection for Breast Cancer: Efficacy and Complication in Developing Countries.

Mohaned O Abass, Mohamed D A Gismalla, Ahmed A Alsheikh, Moawia M A Elhassan

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of global oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mohaned O AbassMohaned O. Abass, Shendi University, Shendi, River Nile State; and Mohamed D.A. Gismalla, Ahmed A. Alsheikh, and Moawia M.A. Elhassan, University of Gezira, Wad Medani, Gezira State, Sudan.
Mohamed D A GismallaMohaned O. Abass, Shendi University, Shendi, River Nile State; and Mohamed D.A. Gismalla, Ahmed A. Alsheikh, and Moawia M.A. Elhassan, University of Gezira, Wad Medani, Gezira State, Sudan.
Ahmed A AlsheikhMohaned O. Abass, Shendi University, Shendi, River Nile State; and Mohamed D.A. Gismalla, Ahmed A. Alsheikh, and Moawia M.A. Elhassan, University of Gezira, Wad Medani, Gezira State, Sudan.
Moawia M A ElhassanMohaned O. Abass, Shendi University, Shendi, River Nile State; and Mohamed D.A. Gismalla, Ahmed A. Alsheikh, and Moawia M.A. Elhassan, University of Gezira, Wad Medani, Gezira State, Sudan.
Shendi University · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAxillary lymph node dissection (ALND) frequently is performed as part of the surgical management of breast cancer as a therapeutic and prognostic index, but increasingly has been perceived as associated with significant complications. Data on efficacy and complications of ALND in Sudan are lacking. The aim of this study was to assess the efficacy and complications of ALND in patients with breast cancer treated with mastectomy and breast-conserving surgery.

methodsWe performed a prospective, hospital-based study in women with invasive breast cancer who underwent modified radical mastectomy or breast-conserving surgery with ALND between September 2014 and August 2015. The efficacy of ALND was defined as retrieval of ≥ 10 lymph nodes. Complications of ALND were assessed objectively and subjectively and defined as either present or absent.

resultsOf 96 patients with breast cancer included in the study, 40 (42%) developed postaxillary clearance complications. The median follow-up time was 18 months (range, 12 to 24 months). Numbness was reported by 21.9% of patients. Seroma was noted in 15.6% and lymphedema in 9.4%. Approximately 9% reported episodes of infection or inflammation at the surgical site. None of the studied factors were found to affect the incidence of complications significantly. Ten or more lymph nodes were retrieved in 81.3% of patients, and nodal metastasis was found in 62.5%.

conclusionThis study shows that the prevalence of undesirable adverse effects after ALND is 42%, with paresthesia and seroma being the most prevalent. The lymphedema prevalence was low in relation to other evaluated symptoms.

Indexed as

AdultAgedAged, 80 and overAxillaBreast NeoplasmsDeveloping CountriesFemaleHumansLymphatic MetastasisLymphedemaLymph Node ExcisionMastectomy, Modified RadicalMastectomy, SegmentalMiddle AgedParesthesiaSeroma

Identifiers

PMID30281378
PMCPMC6223503
OpenAlexW2895351824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.