ReviewBiophysical reviews2018
Switchable DNA-origami nanostructures that respond to their environment and their applications.
Review in Biophysical reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Magnetic DNA Origami Nanorotors.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Signalling and social learning in swarms of robots.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025Article
- DNA origami drives gene expression in a human cell culture system.Scientific reports · 2024Article
- Framework Nucleic Acids-Based VEGF Signaling Activating System for Angiogenesis: A Dual Stimulation Strategy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Synthetic molecular switches driven by DNA-modifying enzymes.Nature communications · 2024Article
- Isothermal self-assembly of multicomponent and evolutive DNA nanostructures.Nature nanotechnology · 2023Article
- In vitro transcription of self-assembling DNA nanoparticles.Scientific reports · 2023Article
- Article
- A single strand: A simplified approach to DNA origami.Frontiers in chemistry · 2023Review
- Single molecule DNA origami nanoarrays with controlled protein orientation.Biophysics reviews · 2022Article
- Rapid DNA origami nanostructure detection and classification using the YOLOv5 deep convolutional neural network.Scientific reports · 2022Article
- Minimizing Cholesterol-Induced Aggregation of Membrane-Interacting DNA Origami Nanostructures.Membranes · 2021Article
- Binding of DNA origami to lipids: maximizing yield and switching via strand displacement.Nucleic acids research · 2021Article
- The biological applications of DNA nanomaterials: current challenges and future directions.Signal transduction and targeted therapy · 2021Review
- Probing the Conformational States of a pH-Sensitive DNA Origami Zipper via Label-Free Electrochemical Methods.Langmuir : the ACS journal of surfaces and colloids · 2021Article
- Engineering Biorthogonal Phage-Based Nanobots for Ultrasensitive,ACS applied bio materials · 2020Article
- The Fusion of Lipid and DNA Nanotechnology.Genes · 2019Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Structural DNA nanotechnology, in which Watson-Crick base pairing drives the formation of self-assembling nanostructures, has rapidly expanded in complexity and functionality since its inception in 1981. DNA nanostructures can now be made in arbitrary three-dimensional shapes and used to scaffold many other functional molecules such as proteins, metallic nanoparticles, polymers, fluorescent dyes and small molecules. In parallel, the field of dynamic DNA nanotechnology has built DNA circuits, motors and switches. More recently, these two areas have begun to merge-to produce switchable DNA nanostructures, which change state in response to their environment. In this review, we summarise switchable DNA nanostructures into two major classes based on response type: molecular actuation triggered by local chemical changes such as pH or concentration and external actuation driven by light, electric or magnetic fields. While molecular actuation has been well explored, external actuation of DNA nanostructures is a relatively new area that allows for the remote control of nanoscale devices. We discuss recent applications for DNA nanostructures where switching is used to perform specific functions-such as opening a capsule to deliver a molecular payload to a target cell. We then discuss challenges and future directions towards achieving synthetic nanomachines with complexity on the level of the protein machinery in living cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.