ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2019
Olfactory bulb atrophy in migraine patients.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Osmophobia in Patients With Migraine: A Systematic Review and Meta-Analysis.World journal of otorhinolaryngology - head and neck surgery · 2025Review
- Article
- Migraine with aura: less control over pain and fragrances?The journal of headache and pain · 2023Article
- Peripheral and Central Smell Regions in Migraine Patients using Maraş Powder (Smokeless Tobacco): A Magnetic Resonance Imaging Evaluation.Journal of neurological surgery. Part B, Skull base · 2022Article
- Review
- Post-COVID-19 neuropsychiatric manifestations among COVID-19 survivors suffering from migraine: a case-control study.The journal of headache and pain · 2022Article
- International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022Review
- Pain, Smell, and Taste in Adults: A Narrative Review of Multisensory Perception and Interaction.Pain and therapy · 2021Review
- Olfactory Bulb Signal Abnormality in Patients with COVID-19 Who Present with Neurologic Symptoms.AJNR. American journal of neuroradiology · 2020Article
- Anosmia: A review in the context of coronavirus disease 2019 and orofacial pain.Journal of the American Dental Association (1939) · 2020Review
- Evaluation of olfactory bulb volume and olfactory sulcus depth in patients with panic disorder and depressive disorder: An MRI study.Indian journal of psychiatryArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveOsmophobia and headache triggered by odors are commonly seen in migraine, and these are symptoms that differentiate migraine from other primary headaches. Since these odor-related symptoms are disease-specific, we aimed to measure the volume of olfactory bulb and depth of olfactory sulcus in migraine patients. PATIENTS AND
methodA total of 93 subjects, consisting of 62 episodic migraine (32 with osmophobia, 30 without osmophobia) patients and 31 healthy controls, were included in this study. Diagnosis and classification of migraine were performed according to the beta version criteria of International Classification of Headache Disorders (ICHD-3 Beta version). Beck depression and beck anxiety inventory were applied to the patients, and the measurement of bilateral olfactory bulb volume (OBV) and olfactory sulcus depth (OSD) was performed manually in the brain magnetic resonance imaging (MRI).
resultsMore significantly in the left OBV, low OBV has been determined in migraine patients compared to the control group (p < 0.001, p = 0.020). When migraine patients with or without osmophobia were compared to the control group; OBV was determined to be the lowest in migraine group with osmophobia, and left-weighted bilateral OBV was determined to be low (p < 0.001, p = 0.046). No statistically significant difference was determined between groups in OSD measurements (p = 0.646, p = 0.490).
conclusionLeft-weighted bilateral OBV atrophy determined in migraine patients may be guiding for the clarification of migraine pathophysiology and enlightening of the relation between migraine and odor.
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