Evidence map›Paper›PMID 30280320›Full record

ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2018

Changes in automated external defibrillator use and survival after out-of-hospital cardiac arrest in the Nijmegen area.

J Nas, J Thannhauser, J J Herrmann, K van der Wulp, P M van Grunsven, N van Royen, M J de Boer, J L Bonnes, M A Brouwer

Open access · diamondAbstract read
In one paragraph

Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Why not try harder to prove that a text message alert system for trained volunteers saves lives after cardiac arrest?Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2023
    Article
  4. Towards individualised treatment of out-of-hospital cardiac arrest patients: an update on technical innovations in the prehospital chain of survival.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Why not try harder to prove that automated external defibrillators save lives?Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

J NasDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands. j.nas@radboudumc.nl.
J ThannhauserDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
J J HerrmannDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
K van der WulpDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
P M van GrunsvenRegional Ambulance Service Gelderland-Zuid, Nijmegen, The Netherlands.
N van RoyenDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
M J de BoerDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
J L BonnesDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
M A BrouwerDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Radboud University Medical Center · NLRadboud University Nijmegen · NLGGD Zuid Limburg · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOut-of-hospital cardiac arrests (OHCAs) are a major healthcare problem. Over the years, several initiatives have contributed to more lay volunteers providing cardiopulmonary resuscitation (CPR) and increased use of automated external defibrillators (AEDs) in the Netherlands. As part of a quality and outcomes program, we registered bystander CPR, AED use and outcome in the Nijmegen area.

methodsProspective resuscitation registry with a study cohort of non-traumatic OHCA cases from 2013-2016 and historical controls from 2008-2011. In line with previous reports, we studied patients transported to the hospital (Radboudumc, Nijmegen, the Netherlands) and excluded arrests witnessed by the emergency medical service (EMS). Primary outcomes were return of spontaneous circulation (ROSC) and survival to discharge.

resultsIn the study cohort (n = 349) the AED was attached more often than in the historical cohort (n = 180): 46% vs. 23% and the proportion of bystander CPR was higher: 78% vs. 63% (both p < 0.001). A higher proportion of patients received an AED shock (39% vs. 15%, p < 0.001) and the number of required shocks by the EMS was lower (2 vs. 4, p = 0.004). Survival to discharge was higher (47% vs. 33%, p = 0.002) without differences in ROSC. The survival benefit was restricted to patients with a shockable initial rhythm. In both cohorts, bystander CPR and AED use were independently associated with survival.

conclusionIn patients admitted after OHCA, survival to discharge has markedly improved to 40-50%, comparable with other Dutch registries. As increased bystander CPR and the doubled use of AEDs seem to have contributed, all civilian-based resuscitation initiatives should be encouraged.

Indexed as

Automated external defibrillatorOut-of-hospital cardiac arrestSurvival

Identifiers

PMID30280320
PMCPMC6288040
OpenAlexW2895173419

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.