ReviewFrontiers in cardiovascular medicine2018
Mapping and Ablation of Idiopathic Ventricular Fibrillation.
Review in Frontiers in cardiovascular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Short-coupled variant of torsade de pointes: A systematic review of case reports and case series.Frontiers in cardiovascular medicine · 2022Pooled it
- 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020Pooled it
- Idiopathic Ventricular Fibrillation Triggered by Purkinje-Related Extrasystoles: State-of-the-Art and Novel Therapeutic Approaches.Journal of cardiovascular electrophysiology · 2026Review
- A Comprehensive Review of a Mechanism-Based Ventricular Electrical Storm Management.Journal of clinical medicine · 2025Review
- Atrial fibrillation nomenclature, definitions, and mechanisms: Position paper from the international Working Group of the Signal Summit.Heart rhythm · 2025Review
- Combining noninvasive electrocardiographic imaging mapping method with fluoroscopic integration module enables the idiopathic ventricular fibrillation ablation triggered by rare premature ventricular contraction.HeartRhythm case reports · 2025Article
- Multidisciplinary Critical Care Management of Electrical Storm: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2023Review
- Idiopathic premature ventricular contraction-triggered ventricular fibrillation: Subcutaneous implantable cardioverter-defibrillator (S-ICD) template matched ablation in the absence of inducible clinical premature ventricular contraction.HeartRhythm case reports · 2023Article
- The circle of reentry: Characteristics of trigger-substrate interaction leading to sudden cardiac arrest.Frontiers in cardiovascular medicine · 2023Article
- Critical Requirements for the Initiation of a Cardiac Arrhythmia in Rat Ventricle: How Many Myocytes?Cells · 2022Article
- Catheter ablation of short-coupled variant of torsade de pointes.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Article
- Long-term freedom from ventricular fibrillation despite persistent Purkinje ectopy after catheter ablation.HeartRhythm case reports · 2022Article
- Developing a Mechanistic Approach to Sudden Death Prevention in Mitral Valve Prolapse.Journal of clinical medicine · 2022Review
- Dominant vector changes during early wavebreak/spiral wave (Wiggers stage 1) in ventricular fibrillation: insights from the analysis of 100 electrophysiology studies.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022Article
- Sex-related differences in incidence, phenotype and risk of sudden cardiac death in inherited arrhythmia syndromes.Frontiers in cardiovascular medicine · 2022Review
- A SPRY1 domain cardiac ryanodine receptor variant associated with short-coupled torsade de pointes.Scientific reports · 2021Article
- Empirical Ablation to Prevent Sequential Purkinje System Recruitment: A Novel Therapy for Idiopathic Ventricular Fibrillation.JACC. Case reports · 2021Article
- Mapping strategies for premature ventricular contractions-activation, voltage, and/or pace map.Herzschrittmachertherapie & Elektrophysiologie · 2021Review
- Why Ablation of Sites With Purkinje Activation Is Antiarrhythmic: The Interplay Between Fast Activation and Arrhythmogenesis.Frontiers in physiology · 2021Article
- Article
Corrections and comments
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Authors and funding
20 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic ventricular fibrillation (IVF) is the main cause of unexplained sudden cardiac death, particularly in young patients under the age of 35. IVF is a diagnosis of exclusion in patients who have survived a VF episode without any identifiable structural or metabolic causes despite extensive diagnostic testing. Genetic testing allows identification of a likely causative mutation in up to 27% of unexplained sudden deaths in children and young adults. In the majority of cases, VF is triggered by PVCs that originate from the Purkinje network. Ablation of VF triggers in this setting is associated with high rates of acute success and long-term freedom from VF recurrence. Recent studies demonstrate that a significant subset of IVF defined by negative comprehensive investigations, demonstrate in fact subclinical structural alterations. These localized myocardial alterations are identified by high density electrogram mapping, are of small size and are mainly located in the epicardium. As reentrant VF drivers are often colocated with regions of abnormal electrograms, this localized substrate can be shown to be mechanistically linked with VF. Such areas may represent an important target for ablation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.