ArticleConservation physiology2018
Assay validation and interspecific comparison of salivary glucocorticoids in three amphibian species.
Article in Conservation physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Pooled it
- Physiological and Skin Microbiome Divergence Among Closely Related Anurans Co-Occurring in Agricultural Wetlands.Ecology and evolution · 2026Article
- Analysis of Reproductive Strategies and Immunological Interactions inAnimals : an open access journal from MDPI · 2025Article
- Validating the underpinnings of water corticosterone measurement for aquatic amphibians.F1000Research · 2025Article
- Dermal glucocorticoids are uncoupled from stress physiology and infection.Conservation physiology · 2025Article
- Why not both? A case study in measuring cortisol and corticosterone.Integrative organismal biology (Oxford, England) · 2025Article
- Validation of non-invasive methods for the measurement of gonadal and inter-renal steroid hormones in a desert-adapted amphibian (Conservation physiology · 2025Article
- Ionizing radiation has negligible effects on the age, telomere length and corticosterone levels of Chornobyl tree frogs.Biology letters · 2024Article
- Framework for multi-stressor physiological response evaluation in amphibian risk assessment and conservation.Frontiers in ecology and evolution · 2024Article
- Evaluation of physiological stress in free-ranging bears: current knowledge and future directions.Biological reviews of the Cambridge Philosophical Society · 2023Review
- Salivary corticosterone measurement in large-billed crows by enzyme-linked immunosorbent assay.The Journal of veterinary medical science · 2023Article
- Exploring water-borne corticosterone collection as a non-invasive tool in amphibian conservation physiology: benefits, limitations and future perspectives.Conservation physiology · 2023Article
- Assay validation of saliva glucocorticoids in Columbia spotted frogs and effects of handling and marking.Conservation physiology · 2023Article
- Article
- Using dermal glucocorticoids to determine the effects of disease and environment on the critically endangered Wyoming toad.Conservation physiology · 2021Article
- Non-invasive methods to measure inter-renal function in aquatic salamanders-correlating fecal corticosterone to the environmental and physiologic conditions of captiveConservation physiology · 2019Article
- Validating the use of dermal secretion as a matrix for monitoring glucocorticoid concentrations in African amphibian species.Conservation physiology · 2019Article
- Non-invasive monitoring of glucocorticoid metabolite concentrations in urine and faeces of the Sungazer (PeerJ · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amphibians are one of the most threatened groups of species, facing stressors ranging from habitat degradation and pollution to disease and overexploitation. Stress hormones (glucocorticoids, GCs) provide one quantitative metric of stress, and developing non-invasive methods for measuring GCs in amphibians would clarify how diverse environmental stressors impact individual health in this taxonomic group. Saliva is an advantageous matrix for quantifying GCs, as it is sampled less invasively than plasma while still detecting both baseline and acute elevation of GCs within a short timeframe. Little work has employed this method in amphibian species, and it has never been pharmacologically and biologically validated. Here, we conduct analytical, pharmacological and biological validation experiments for measuring salivary corticosterone in three amphibian species: the American bullfrog (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.