Evidence map›Paper›PMID 30279739›Full record

ArticleTheranostics2018

Céline S Gonçalves, Joana Vieira de Castro, Marta Pojo, Eduarda P Martins, Sandro Queirós, Emmanuel Chautard, Ricardo Taipa, Manuel Melo Pires, Afonso A Pinto, Fernando Pardal and 6 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Emerging roles and biomarker potential of WNT6 in human cancers.Cell communication and signaling : CCS · 2024
    Review
  7. Article
  8. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  9. The Roles of Secreted Wnt Ligands in Cancer.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Céline S GonçalvesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Joana Vieira de CastroLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Marta PojoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Eduarda P MartinsLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Sandro QueirósLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Emmanuel ChautardUniversité Clermont Auvergne, INSERM, U1240 IMoST, 63000 Clermont Ferrand, France.
Ricardo TaipaNeuropathology Unit, Department of Neurosciences, Centro Hospitalar do Porto, Porto, Portugal.
Manuel Melo PiresNeuropathology Unit, Department of Neurosciences, Centro Hospitalar do Porto, Porto, Portugal.
Afonso A PintoDepartment of Neurosurgery, Hospital Escala Braga, Sete Fontes - São Victor 4710-243 Braga, Portugal.
Fernando PardalDepartment of Pathology, Hospital Escala Braga, Sete Fontes - São Victor 4710-243 Braga, Portugal.
Carlos CustódiaInstituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Cláudia C FariaInstituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Carlos ClaraMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos - S. Paulo, Brazil.
Rui M ReisLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Nuno SousaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Bruno M CostaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
University of Minho · PTCentro Hospitalar do Porto · PTHospital Braga · PTUniversity of Lisbon · PTCentre Jean Perrin · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is a universally fatal brain cancer, for which novel therapies targeting specific underlying oncogenic events are urgently needed. While the WNT pathway has been shown to be frequently activated in GBM, constituting a potential therapeutic target, the relevance of WNT6, an activator of this pathway, remains unknown.

Indexed as

AnimalsAntineoplastic AgentsBiomarkersCell Line, TumorCell MovementCell ProliferationCell SurvivalDisease Models, AnimalDrug Resistance, NeoplasmGene ExpressionGene Expression ProfilingGene Knockdown TechniquesGlioblastomaHumansMicePrognosisAntineoplastic AgentsBiomarkersProto-Oncogene ProteinsTemozolomideWNT6 protein, humanWnt6 protein, mouseWnt ProteinsbiomarkerglioblastomaoncogeneprognosisWNT6WNT pathway

Identifiers

PMID30279739
PMCPMC6160775
OpenAlexW2890251762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.