Evidence map›Paper›PMID 30279738›Full record

ArticleTheranostics2018

Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis.

Bo Youn Choi, Yuri Choi, Jong-Sung Park, Li-Jung Kang, Seung Hyun Baek, Jin Su Park, Gahee Bahn, Yoonsuk Cho, Hark Kyun Kim, Jihoon Han and 10 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Another Notch in the Belt of Rheumatoid Arthritis.Arthritis & rheumatology (Hoboken, N.J.) · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Notch signaling pathway: architecture, disease, and therapeutics.Signal transduction and targeted therapy · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 2 countries.

Bo Youn ChoiSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Yuri ChoiSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Jong-Sung ParkSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Li-Jung KangDepartment of Pharmacology, Ajou University School of Medicine, Suwon, Korea.
Seung Hyun BaekSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Jin Su ParkSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Gahee BahnSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Yoonsuk ChoSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Hark Kyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Jihoon HanSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Jae Hoon SulSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Sang-Ha BaikSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Dong Hoon HyunDepartment of Life Science, Ewha Womans University, Seoul, Korea.
Thiruma V ArumugamSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Siyoung YangDepartment of Pharmacology, Ajou University School of Medicine, Suwon, Korea.
Jeung-Whan HanSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Young Mo KangDepartment of Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, Korea.
Yong-Woo ChoDepartment of Chemical Engineering, Hanyang University, Ansan, Korea.
Jae Hyung ParkDepartment of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Korea.
Dong-Gyu JoSchool of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Sungkyunkwan University · KRAjou University · KRSamsung (South Korea) · KREwha Womans University · KRHanyang University · KRKyungpook National University · KRNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibition of Notch signalling has shown anti-inflammatory properties

Indexed as

AnimalsArthritis, RheumatoidDisease Models, AnimalFlow CytometryGene Knockdown TechniquesMice, Inbred C57BLMice, Inbred DBAMice, TransgenicReceptor, Notch1Signal TransductionT-Lymphocytes, RegulatoryNotch1 protein, mouseReceptor, Notch1CAIACIANotch1rheumatoid arthritisTregγ-secretase

Identifiers

PMID30279738
PMCPMC6160763
OpenAlexW2890666563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.