Evidence map›Paper›PMID 30279729›Full record

ArticleTheranostics2018

Hypoxia-induced up-regulation of VASP promotes invasiveness and metastasis of hepatocellular carcinoma.

Zhikui Liu, Yufeng Wang, Changwei Dou, Meng Xu, Liankang Sun, Liang Wang, Bowen Yao, Qing Li, Wei Yang, Kangsheng Tu and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 101 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 1 synthesis or guideline pooled it, 168 citations in OpenAlex.

  1. The impact of particulate matter 2.5 on the risk of hepatocellular carcinoma: a meta-analysis.International archives of occupational and environmental health · 2022
    Pooled it
  2. Article
  3. Development of a prognostic prediction model incorporatingJournal of gastrointestinal oncology · 2026
    Article
  4. Article
  5. Review
  6. Understanding how hypoxia contributes to liver cancer stem cells maintenance.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. IntratumorCurrent research in microbial sciences · 2025
    Article
  19. Article
  20. Review

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Zhikui LiuDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Yufeng WangDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Changwei DouDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Meng XuDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Liankang SunDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Liang WangDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Bowen YaoDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Qing LiDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Wei YangDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Kangsheng TuDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
Qingguang LiuDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an 710061, China.
First Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HypoxiaUp-RegulationAdaptor Proteins, Signal TransducingAnimalsBiological AssayBlotting, WesternCarcinoma, HepatocellularCell Adhesion MoleculesCell Line, TumorCell MovementChromatin ImmunoprecipitationDisease Models, AnimalGene Expression ProfilingHumansHypoxia-Inducible Factor 1, alpha SubunitImmunohistochemistryAdaptor Proteins, Signal TransducingCell Adhesion MoleculesCRKL proteinHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitMicrofilament ProteinsMicroRNAsMIRN204 microRNA, humanNuclear ProteinsPhosphoproteinsVasodilator-Stimulated PhosphoproteinCRKLhepatocellular carcinomahypoxia microenvironmentmetastasisVASP

Identifiers

PMID30279729
PMCPMC6160773
OpenAlexW2891235534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.