Evidence map›Paper›PMID 30279540›Full record

ArticleScientific reports2018

Pyrophosphate inhibits gluconeogenesis by restricting UDP-glucose formation in vivo.

Ali Ferjani, Kensuke Kawade, Mariko Asaoka, Akira Oikawa, Takashi Okada, Atsushi Mochizuki, Masayoshi Maeshima, Masami Yokota Hirai, Kazuki Saito, Hirokazu Tsukaya

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Development of phytochemical genomics: From decoding metabolome to functional genomics and biotechnology of plant metabolism.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025
    Review
  6. Exploring Redox Modulation of Plant UDP-Glucose Pyrophosphorylase.International journal of molecular sciences · 2023
    Article
  7. Roles of type II HFrontiers in plant science · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Magnesium Signaling in Plants.International journal of molecular sciences · 2021
    Review
  15. Article
  16. The HFrontiers in plant science · 2020
    Article
  17. Lack of Vacuolar HFrontiers in plant science · 2020
    Article
  18. Article
  19. Article
  20. Vacuolar Proton Pyrophosphatase Is Required for High Magnesium Tolerance inInternational journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Ali FerjaniDepartment of Biology, Tokyo Gakugei University, Koganei, Tokyo, 184-8501, Japan. ferjani@u-gakugei.ac.jp.ORCID http://orcid.org/0000-0003-1157-3261
Kensuke KawadeOkazaki Institute for Integrative Bioscience, Okazaki, Aichi, 444-8787, Japan.ORCID http://orcid.org/0000-0003-1701-4567
Mariko AsaokaLaboratory of Cell Dynamics, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, 464-8601, Japan.
Akira OikawaRIKEN Center for Sustainable Resource Science, Yokohama, 230-0045, Japan.
Takashi OkadaTheoretical Biology Laboratory, RIKEN, Wako, 351-0198, Japan.
Atsushi MochizukiTheoretical Biology Laboratory, RIKEN, Wako, 351-0198, Japan. mochi@riken.jp.
Masayoshi MaeshimaLaboratory of Cell Dynamics, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, 464-8601, Japan.ORCID http://orcid.org/0000-0002-1611-5481
Masami Yokota HiraiRIKEN Center for Sustainable Resource Science, Yokohama, 230-0045, Japan.
Kazuki SaitoRIKEN Center for Sustainable Resource Science, Yokohama, 230-0045, Japan.
Hirokazu TsukayaOkazaki Institute for Integrative Bioscience, Okazaki, Aichi, 444-8787, Japan.ORCID http://orcid.org/0000-0002-4430-4538
RIKEN · JPTokyo Gakugei University · JPChiba University · JPNagoya University · JPNational Institute for Basic Biology · JPNational Institutes of Natural Sciences · JPRIKEN Center for Sustainable Resource Science · JPYamagata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyrophosphate (PPi) is produced by anabolic reactions and serves as an energy donor in the cytosol of plant cells; however, its accumulation to toxic levels disrupts several common biosynthetic pathways and is lethal. Before acquiring photosynthetic capacity, young seedlings must endure a short but critical heterotrophic period, during which they are nourished solely by sugar produced from seed reserves by the anabolic process of gluconeogenesis. Previously, we reported that excess PPi in H

Indexed as

GluconeogenesisArabidopsisArabidopsis ProteinsCarbon-Carbon Double Bond IsomerasesDiphosphatesHemiterpenesInorganic PyrophosphataseMetabolomicsPlants, Genetically ModifiedSeedlingsUridine Diphosphate GlucoseArabidopsis ProteinsAVP1 protein, ArabidopsisCarbon-Carbon Double Bond IsomerasesDiphosphatesdiphosphoric acidHemiterpenesInorganic Pyrophosphataseisopentenyldiphosphate delta-isomeraseUridine Diphosphate Glucose

Identifiers

PMID30279540
PMCPMC6168488
OpenAlexW2892984827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.