Evidence map›Paper›PMID 30279318›Full record

ArticleActa crystallographica. Section F, Structural biology communications2018

Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence.

Ruby Sharma, Shanti P Gangwar, Ajay K Saxena

Erratum issuedAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. How acidic amino acid residues facilitate DNA target site selection.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ruby SharmaStructural Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110 067, India.
Shanti P GangwarStructural Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110 067, India.
Ajay K SaxenaStructural Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110 067, India.

Funding

Department of Science and Technology, Ministry of Science and Technology SR/SO/HS-05/2009
6 · The paper itself

Abstract

ERG3 (ETS-related gene) is a member of the ETS (erythroblast transformation-specific) family of transcription factors, which contain a highly conserved DNA-binding domain. The ETS family of transcription factors differ in their binding to promoter DNA sequences, and the mechanism of their DNA-sequence discrimination is little known. In the current study, crystals of the ETSi domain (the ETS domain of ERG3 containing a CID motif) in space group P4

Indexed as

Amino Acid SequenceAnimalsBinding SitesCloning, MolecularCrystallography, X-RayDNADNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsEscherichia coliGene ExpressionGenetic VectorsHumansModels, MolecularNucleic Acid ConformationPromoter Regions, GeneticDNADNA-Binding ProteinsDrosophila ProteinsEip74EF protein, DrosophilaFLI1 protein, humanProto-Oncogene Protein c-fli-1Recombinant ProteinsTranscription Factorscomparative structure analysisE74 promoter DNAERG3ETS transcription factorprostate cancerX-ray structure

Identifiers

PMID30279318
PMCPMC6168766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.