Evidence map›Paper›PMID 30279286›Full record

ArticlemBio2018

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus

Vera Voltersen, Matthew G Blango, Sahra Herrmann, Franziska Schmidt, Thorsten Heinekamp, Maria Strassburger, Thomas Krüger, Petra Bacher, Jasmin Lother, Esther Weiss and 13 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 68 citations in OpenAlex.

  1. Temperature duringbioRxiv : the preprint server for biology · 2026
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  3. Oxidoreductase geneMicrobiology spectrum · 2026
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  6. mBio · 2025
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  7. Macrophage vacuolar ATPase (v-ATPase) function controlsbioRxiv : the preprint server for biology · 2025
    Article
  8. Proteomic Changes inJournal of proteome research · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Conidium Specific Polysaccharides inJournal of fungi (Basel, Switzerland) · 2023
    Article
  16. Review
  17. Review
  18. Article
  19. Distinct Cohorts ofFrontiers in cellular and infection microbiology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 8 institutions in 2 countries.

Vera Voltersen *Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.
Matthew G Blango *Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.ORCID 0000-0001-8015-9019
Sahra HerrmannInstitute for Medical Microbiology, University Medical Center, Göttingen, Germany.
Franziska SchmidtDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.
Thorsten HeinekampDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.
Maria StrassburgerTransfer Group Anti-infectives, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.
Thomas KrügerDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.
Petra BacherInstitute of Clinical Molecular Biology, Christian-Albrechts University Kiel, Kiel, Germany.
Jasmin LotherMedical Clinic and Policlinic II, University Clinic Würzburg, Würzburg, Germany.
Esther WeissMedical Clinic and Policlinic II, University Clinic Würzburg, Würzburg, Germany.
Kerstin HünnigerInstitute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.
Hong LiuDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Peter HortschanskyDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.
Alexander ScheffoldInstitute of Immunology, Christian-Albrechts University Kiel & Universitätsklinik Schleswig-Holstein, Kiel, Germany.
Jürgen LöfflerMedical Clinic and Policlinic II, University Clinic Würzburg, Würzburg, Germany.ORCID 0000-0001-6619-1100
Sven KrappmannMicrobiology Institute-Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen and Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Sandor NietzscheCenter for Electron Microscopy, Jena University Hospital, Jena, Germany.
Oliver KurzaiInstitute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.
Hermann EinseleInternal Medicine II, University Hospital Würzburg, Würzburg, Germany.
Olaf KniemeyerDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.ORCID 0000-0002-9493-6402
Scott G FillerDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Utz ReichardInstitute for Medical Microbiology, University Medical Center, Göttingen, Germany.
Axel A BrakhageDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany axel.brakhage@leibniz-hki.de.ORCID 0000-0002-8814-4193
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEUniversitätsklinikum Würzburg · DEChristian-Albrechts-Universität zu Kiel · DEUniversitätsmedizin Göttingen · DEUniversity of California, Los Angeles · USUniversity of Würzburg · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEJena University Hospital · DE

Funding

Transcriptional regulation of A. fumigatus virulenceR01AI073829 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G · 2007 to 2015
$2.8M
Endothelial invasion by yeast-phase CandidaR01AI124566 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MITCHELL, AARON P · 2016 to 2020
$2.7M
GENE EXPRESSION AND FUNCTION IN ASPERGILLOSISR56AI111836 · NIAID · CARNEGIE-MELLON UNIVERSITY · PI FILLER, SCOTT G, MITCHELL, AARON P · 2014 to 2014
$513k
NIAID NIH HHS R01 AI073829NIAID NIH HHS R01 AI124566NIAID NIH HHS R56 AI111836
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

A549 CellsAnimalsAspergillosisAspergillus fumigatusCell WallChromatography, LiquidDendritic CellsEndocytosisEpithelial CellsFemaleFungal ProteinsHumansImmunocompromised HostMembrane ProteinsMiceNeutrophil ActivationFungal ProteinsMembrane ProteinsProteomeVirulence FactorsAspergillus fumigatusCcpAdendritic cellepithelial cellimmune responsemass spectrometryneutrophilresting conidiasurface proteomeswollen conidiaT cellstrypsin shaving

Identifiers

PMID30279286
PMCPMC6168859
OpenAlexW2894964423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.