Evidence map›Paper›PMID 30279282›Full record

ArticlemBio2018

Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly.

Xiaoyu Sun, Serban L Ilca, Juha T Huiskonen, Minna M Poranen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Xiaoyu SunMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Serban L IlcaDivision of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Juha T HuiskonenMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland juha.huiskonen@helsinki.fi minna.poranen@helsinki.Fi.
Minna M PoranenMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland juha.huiskonen@helsinki.fi minna.poranen@helsinki.Fi.
University of Helsinki · FICentre for Human Genetics · GBUniversity of Oxford · GB

Funding

Wellcome TrustWellcome Trust 060208/Z/00/ZWellcome Trust 093305/Z/10/ZWellcome Trust 109135/Z/15/AWellcome Trust 203141/Z/16/Z
6 · The paper itself

Abstract

Double-stranded RNA (dsRNA) viruses package several RNA-dependent RNA polymerases (RdRp) together with their dsRNA genome into an icosahedral protein capsid known as the polymerase complex. This structure is highly conserved among dsRNA viruses but is not found in any other virus group. RdRp subunits typically interact directly with the main capsid proteins, close to the 5-fold symmetric axes, and perform viral genome replication and transcription within the icosahedral protein shell. In this study, we utilized

Indexed as

Virus AssemblyVirus ReplicationAmino Acid SubstitutionBacteriophage phi 6Capsid ProteinsDNA Mutational AnalysisProtein BindingProtein MultimerizationRNA-Dependent RNA PolymeraseTranscription, GeneticCapsid ProteinsRNA-Dependent RNA Polymerasebacteriophage assemblycystovirusdouble-stranded RNA virusPseudomonas phage phi6RNA-dependent RNA polymerasevirus assembly

Identifiers

PMID30279282
PMCPMC6168860
OpenAlexW2895771969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.