ArticleJournal of lipid research2018
Comprehensive shotgun lipidomics of human meibomian gland secretions using MS/MS
Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed.
- Intracrine androgen metabolism in the meibomian gland: regulation, circadian control, and implications in dry eye disease.Endocrine journal · 2026Review
- Direct Correlation of Levels of Meibum Cholesteryl Esters, Hydrocarbon Chain Saturation, and Protein With Lipid Structure, in Relation to Age and Dry Eye.Investigative ophthalmology & visual science · 2026Article
- Stability and Compressibility of Tear Film Lipid Layer: Impact of Benzalkonium Chloride Presence.bioRxiv : the preprint server for biology · 2026Article
- A Novel Rat Model for Human Meibomian Gland Dysfunction and Ocular Rosacea.Investigative ophthalmology & visual science · 2026Article
- Epigallocatechin Gallate as a Molecular Therapeutic in Heart Failure and Cardio-Oncology: Mechanistic Pathways and Translational Perspectives.International journal of molecular sciences · 2025Review
- Comprehensive lipid analysis of human meibum and tears.Scientific reports · 2025Article
- One Step Closer to a Molecular Level Understanding of the Tear Film Lipid Layer by Surface X-ray Scattering.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Identification of meibomian gland testosterone metabolites produced by tissue-intrinsic intracrine deactivation activity.iScience · 2025Article
- Changes in Human Meibum Lipid Composition Related to the Presence and Severity of Meibomian Gland Dysfunction.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2024Article
- Article
- Evaluation of the effects of latanoprost and benzalkonium chloride on the cell viability and nonpolar lipid profile produced by human meibomian gland epithelial cells in culture.Molecular vision · 2023Article
- Dairy Milk Casein and Whey Proteins Differentially Alter the Postprandial Lipidome in Persons with Prediabetes: A Comparative Lipidomics Study.Journal of agricultural and food chemistry · 2022Article
- Human meibum and tear film derived cholesteryl and wax esters in meibomian gland dysfunction and tear film structure.The ocular surface · 2022Article
- Comparative Metabolomic Study ofInternational journal of molecular sciences · 2021Article
- A spectroscopic approach to measuring meibum lipid composition and conformation in donors with Sjӧgren's syndrome.Experimental eye research · 2021Article
- A spectroscopic study of the composition and conformation of cholesteryl and wax esters purified from meibum.Chemistry and physics of lipids · 2021Article
- Human Meibum and Tear Film Derived (O-Acyl)-Omega-Hydroxy Fatty Acids as Biomarkers of Tear Film Dynamics in Meibomian Gland Dysfunction and Dry Eye Disease.Investigative ophthalmology & visual science · 2021Article
- Human meibum and tear film derived (O-acyl)-omega-hydroxy fatty acids in meibomian gland dysfunction.The ocular surface · 2021Article
- Triacylglycerol lipidome from human meibomian gland epithelial cells: Description, response to culture conditions, and perspective on function.Experimental eye research · 2021Article
- Saturation of cholesteryl esters produced by human meibomian gland epithelial cells after treatment with rosiglitazone.The ocular surface · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
Abstract
The lipid composition of human meibomian gland secretions (meibum) has been analyzed using both targeted and untargeted mass spectrometric approaches, each of which has its advantages and disadvantages. Herein we report the results of shotgun lipidomic profiling of human meibum using a new approach that combines the advantages of targeted and untargeted analyses to yield highly sensitive and comprehensive profiles. Samples containing an estimated 7-13 µg (8-16 nL) of human meibum lipids were analyzed using MS/MS
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.