Evidence map›Paper›PMID 30279176›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Notch2-dependent DC2s mediate splenic germinal center responses.

Carlos G Briseño, Ansuman T Satpathy, Jesse T Davidson, Stephen T Ferris, Vivek Durai, Prachi Bagadia, Kevin W O'Connor, Derek J Theisen, Theresa L Murphy, Kenneth M Murphy

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 83 citations in OpenAlex.

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  5. Tim-3-targeted vaccines overcome tumor immunosuppression and reduce cDC1 dependence to elicit potent anti-tumor immunity.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Carlos G BriseñoDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Ansuman T SatpathyCenter for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA 94305.
Jesse T DavidsonDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Stephen T FerrisDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Vivek DuraiDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Prachi BagadiaDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Kevin W O'ConnorDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Derek J TheisenDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Theresa L MurphyDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Kenneth M MurphyDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110; kmurphy@wustl.edu.
Washington University in St. Louis · USStanford University · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
TRAINING PROGRAM IN IMMUNOLOGY AND IMMUNOGENETICST32AI007163 · NIAID · WASHINGTON UNIVERSITY · PI Kenneth M Murphy, Kodi S Ravichandran · 1985 to 2026
$14.8M
SURGICAL ONCOLOGY TRAINING GRANTT32CA009621 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN, William E. Gillanders · 1988 to 2026
$12.9M
TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCERT32CA009547 · NCI · WASHINGTON UNIVERSITY · PI ROBERT DAVID SCHREIBER · 1986 to 2026
$12.1M
The role of cross-presentation of self-antigens by dendritic cells in type 1 diabetesF30DK108498 · NIDDK · WASHINGTON UNIVERSITY · PI DURAI, VIVEK · 2015 to 2017
$109k
Howard Hughes Medical InstituteNCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NCI NIH HHS T32 CA009547NCI NIH HHS T32 CA009621NIAID NIH HHS T32 AI007163NIDDK NIH HHS F30 DK108498
6 · The paper itself

Abstract

CD4

Indexed as

AnimalsAntigen PresentationB-LymphocytesCell DifferentiationCells, CulturedDendritic CellsErythrocytesGerminal CenterImmunity, HumoralKruppel-Like Factor 4Lymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutReceptor, Notch2SheepKlf4 protein, mouseKruppel-Like Factor 4Notch2 protein, mouseReceptor, Notch2dendritic cellgerminal centerT follicular helper cell

Identifiers

PMID30279176
PMCPMC6196531
OpenAlexW2894592421

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.