ArticleThe Journal of international medical research2019
Clinical characteristics and prognosis of idiopathic pulmonary hemosiderosis in pediatric patients.
Article in The Journal of international medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 66 citations in OpenAlex.
- The Role of Macrophage M1/M2 Polarization Imbalance in the Pathogenesis of Immune Associated Diffuse Alveolar Hemorrhage: Evidence From the Study of Human Clinical Specimens.Pediatric pulmonology · 2026Article
- When history can mislead a physician: a challenging case report of idiopathic pulmonary hemosiderosis-A case report and review of the literature.Journal of medical case reports · 2026Review
- Case Report: Effective use of rituximab in children with steroid-resistant/dependent idiopathic pulmonary hemosiderosis: description of two cases and literature review.Frontiers in pediatrics · 2026Article
- The role of arterial embolization in pediatric Idiopathic Pulmonary Hemosiderosis: a case report and literature review.Respiratory medicine case reports · 2026Article
- Idiopathic pulmonary hemosiderosis: A pediatric case report.Respiratory medicine case reports · 2025Article
- Clinical features and risk factors for recurrence of idiopathic pulmonary hemosiderosis in children.BMC pulmonary medicine · 2024Observational
- Pulmonary siderosis complicated with severe mycoplasma pneumoniae pneumonia: A case report.Respiratory medicine case reports · 2024Article
- Idiopathic pulmonary haemosiderosis misdiagnosed as haemolytic anaemia: a case report.The Journal of international medical research · 2023Article
- Clinical Presentation and Treatment of Juvenile Idiopathic Arthritis Combined with Lung Disease: A Narrative Review.Rheumatology and therapy · 2023Review
- Diffuse alveolar hemorrhage in children with interstitial lung disease: Determine etiologies!Pediatric pulmonology · 2023Article
- Diffuse alveolar haemorrhage in children: an international multicentre study.ERJ open research · 2023Article
- Diffuse alveolar haemorrhage in children hospitalised in a tertiary‑level hospital: A retrospective descriptive study.African journal of thoracic and critical care medicine · 2023Article
- Prevalence of autoantibodies in pediatric patients with idiopathic pulmonary hemosiderosis: a scoping review of the literature in the period 1980-2021.Clinical rheumatology · 2022Article
- Proposed Pathogenesis of Diffuse Alveolar Hemorrhage in Idiopathic Pulmonary Hemosiderosis.Lung · 2022Review
- Diffuse alveolar hemorrhage in children with trisomy 21.Pediatric rheumatology online journal · 2021Review
- Idiopathic pulmonary hemosiderosis: a review of the treatments used during the past 30 years and future directions.Clinical rheumatology · 2021Review
- Pulmonary Nocardia infection in a child with idiopathic pulmonary hemosiderosis.BMC pulmonary medicine · 2021Article
- Possible association of idiopathic pulmonary hemosiderosis with rheumatoid arthritis: A case report.Experimental and therapeutic medicine · 2020Article
- Idiopathic Pulmonary Hemosiderosis as a Mimic of Pulmonary Vasculitis: A Case Report and Review of the Literature.Current allergy and asthma reports · 2020Review
- Successful Liposteroid Therapy for a Recurrent Idiopathic Pulmonary Hemosiderosis with Down Syndrome.Case reports in pediatrics · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to analyze the clinical characteristics and prognosis of pediatric idiopathic pulmonary hemosiderosis (IPH).
methodsPediatric IPH cases that were diagnosed at West China Second University Hospital, Sichuan University between 1996 and 2017 were reviewed. Follow-up data from 34 patients were collected.
resultsA total of 107 patients were included (42 boys and 65 girls). The median age was 6 years at diagnosis. The main manifestations of the patients were as follows: anemia (n = 100, 93.45%), cough (n = 68, 63.55%), hemoptysis (n = 61, 57%), fever (n = 23, 21.5%), and dyspnea (n = 23, 21.5%). There were relatively few pulmonary signs. The positive rates of hemosiderin-laden macrophages in sputum, gastric lavage fluid, and bronchoalveolar lavage fluid were 91.66%, 98.21%, and 100%, respectively. Seventy-nine patients were misdiagnosed. A total of 105 patients were initially treated with glucocorticoids, among whom 102 survived and three died. Among the followed up patients, two died and 32 survived, among whom 10 presented with recurrent episodes.
conclusionsThe classic triad of pediatric IPH is not always present. The rates of misdiagnosis and recurrence of IPH are high. Early recognition and adequate immunosuppressive therapy are imperative for improving prognosis of IPH.
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