Evidence map›Paper›PMID 30278572›Full record

ArticleMedicine2018

Chinese herbal medicine for opioid induced constipation in cancer patients: Protocol for a systematic review.

Shuo Qi, Hezheng Lai, Yayue Zhang, Qing Dong, Xiaoshu Zhu

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Shuo QiDongzhimen Hospital Affiliate to Beijing University of Chinese Medicine, Beijing, China.
Hezheng LaiSchool of Health and Science, Western Sydney University, Campbelltown, New South Wales.
Yayue ZhangDongzhimen Hospital Affiliate to Beijing University of Chinese Medicine, Beijing, China.
Qing DongDongzhimen Hospital Affiliate to Beijing University of Chinese Medicine, Beijing, China.
Xiaoshu ZhuSchool of Health and Science, Western Sydney University, Campbelltown, New South Wales.
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNCamden and Campbelltown Hospitals · AUWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOpioid induced constipation (OIC) is a symptom that is commonly encountered in cancer pain management. Chinese herbal medicine (CHM) has been widely used to improve OIC in China. Many clinical trials indicate that CHM could improve OIC. In this systematic review, we aim to evaluate the effectiveness and safety of CHM for OIC in cancer patients.

methodsWe will search the following electronic databases for randomized controlled trials to evaluate the effectiveness and safety of CHM for OIC in cancer patients: CENTRAL, EMBASE, MEDILINE, CINAHL and China National Knowledge Infrastructure. Each database will be searched from inception to June 2018. The entire process will include study selection, data extraction, risk of bias assessment and meta-analyses.

resultsThis proposed study will evaluate the effectiveness and safety of CHM for OIC. The outcomes will include change in bowel movements, quality of life and adverse events.

conclusionsThis proposed systematic review will evaluate the existing evidence on the effectiveness and safety of CHM for OIC in cancer patients. DISSEMINATION AND ETHICS: The results of this review will be disseminated through peer-reviewed publication. Because all of the data used in this systematic review and meta-analysis has been published, this review does not require ethical approval. Furthermore, all data will be analyzed anonymously during the review process.

Indexed as

Analgesics, OpioidCancer PainConstipationDrugs, Chinese HerbalHumansPublication BiasQuality of LifeSystematic Reviews as TopicAnalgesics, OpioidDrugs, Chinese Herbal

Identifiers

PMID30278572
PMCPMC6181624
OpenAlexW2919070345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.