Evidence map›Paper›PMID 30278535›Full record

ArticleMedicine2018

Recurrent cerebral microbleeds with acute stroke symptoms: A case report.

Pahn Kyu Choi, Ji Yeon Chung, Seung Jae Lee, Hyun Goo Kang

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pahn Kyu ChoiDepartment of Neurology, Chosun University School of Medicine and Hospital, Gwang-ju.
Ji Yeon ChungDepartment of Neurology, Chosun University School of Medicine and Hospital, Gwang-ju.
Seung Jae LeeDepartment of Chemistry.
Hyun Goo KangDepartment of Neurology, Chonbuk National University School of Medicine and Hospital, Jeonju, South Korea.
Chosun University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleCerebral microbleeds are lesions that appear as round low signal intensity areas with a diameter of 2-5 mm on gradient echo T2-weighted sequence magnetic resonance imaging. Cerebral microblees are hemorrhages found in the brain parenchyma and they are caused by the extravasation of the blood. Although more patients with ischemic stroke are found to have cerebral microbleeds, only a few studies have evaluated other neurologic abnormalities outside of cognitive dysfunction due to cerebral microbleeds. PATIENT CONCERNS: A 73-year-old female patient had only a lacunar infarction with the development of a new microbleed whenever a new neurologic symptom occurred, without the occurrence of acute ischemic stroke. DIAGNOSES: A 73-year-old female patient diagnosed symptomatic cerebral microbleeds.

interventionsBrain magnetic resonance imaging was taken within a few hours of the occurrence of a new symptom and we confirmed increased cerebral microbleeds in the ventral-posterolateral area of the thalamus, consistent with the symptoms. OUTCOMES: This case study is meaningful because it proves that repeated occurrences of cerebral microbleeds in a specific area can induce acute ischemic stroke-like symptoms. LESSONS: Cerebral microbleeds have been considered to be asymptomatic lesions thus far. However, recent studies have reported the association of cerebral microbleeds with neurological symptoms including cognitive dysfunction. This study confirmed the presence of newly formed cerebral microbleeds through imaging follow-ups whenever a symptom occurred.

Indexed as

AgedBasal Ganglia Cerebrovascular DiseaseBrainCerebral HemorrhageCilostazolCognitive DysfunctionDiffusion Magnetic Resonance ImagingFemaleHumansNeuroprotective AgentsRecurrenceStrokeTetrazolesVentral Thalamic NucleiCilostazolNeuroprotective AgentsTetrazoles

Identifiers

PMID30278535
PMCPMC6181546
OpenAlexW2895232241

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.