Evidence map›Paper›PMID 30278483›Full record

SynthesisMedicine2018

Prevalence and determinants of depression in caregivers of cancer patients: A systematic review and meta-analysis.

Hai-Mei Geng, Dong-Mei Chuang, Fang Yang, Yang Yang, Wei-Min Liu, Li-Hui Liu, Hong-Mei Tian

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 217 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
217citing papers in PubMed, 8 pooled it
60.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05859880 nacompletednot on this mapstarted 2023, after this paper: background citation

A Community-based Video-conference-delivered Expressive Writing Intervention for Caregivers of Persons With Cancer

TypeinterventionalSponsorArizona State UniversityRan2023 to 2025Enrolled100ConditionsQuality of Life, Distress, EmotionalArmsExpressive writing intervention
NCT06433349 recruitingnot on this mapstarted 2024, after this paper: background citation

A Multi-center Investigation of Family Health, Needs, Perceived Support, Self-efficacy and Quality of Life During the Cancer Trajectory: A Longitudinal Mixed Methods Study Among Danish Cancer Patients and Their Caregivers

TypeobservationalSponsorOdense University HospitalRan2024 to 2028Enrolled240ConditionsBreast Cancer, Prostate Cancer, Colorectal Cancer, Hematologic NeoplasmsArmsSurvey and interviews
3 · Its place in the literature

Who cites it

217 citing papers in PubMed, 8 syntheses or guidelines pooled it, 403 citations in OpenAlex.

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  10. Investigating the effect of web-based education on positive mental health of family caregivers of breast cancer patients: a quasi-experimental study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  11. The effect of the Emotional Freedom Technique (EFT) on pain and depression in cancer patients: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  13. A sequential multiple assignment randomized trial of symptom management for cancer survivors during treatment and their informal caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  14. Resilience, preparedness, and distress among family caregivers of patients with advanced cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Trial
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  17. Exploring the understanding and management of anxiety from cancer in Latino/a older adults and their caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  20. Article

157 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hai-Mei GengDepartment of Oncology.
Dong-Mei ChuangDepartment of Glioma.
Fang YangDepartment of Oncology.
Yang YangDepartment of Oncology.
Wei-Min LiuDepartment of Oncology.
Li-Hui LiuDepartment of Nursing, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Hong-Mei TianDepartment of Nursing, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Beijing Shijitan Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAim of this study was to estimate the prevalence rate of depression in cancer patient caregivers and to identify factors affecting depression and quality of life of cancer caregivers.

methodsRelevant research articles were retrieved after literature search in several electronic databases. Random effects meta-analyses were performed to obtain pooled estimates of the prevalence rates of depression and anxiety; their respective scores, and quality of life scores. Significant relationships between depression and factors related to depression and quality of life reported in individual studies were identified.

resultsThirty studies were included. Overall, 21,149 caregivers were appraised in these studies (age 52.65 years [95% CI: 49.65, 55.65]; 31.14% [28.40, 33.89] men). The prevalence of depression and anxiety were 42.30% [33.31, 51.29] % and 46.55% [35.59, 57.52], respectively. Quality of life score, as measured with Caregiver Quality of Life-Cancer scale was 64.55 [47.44, 81.66]. Patient's condition, caregiving burden, duration of caregiving, spouse caregiver, caregiver being unemployed, caregiver with chronic disease, caregiver's sleep quality, caregiver's avoidance, financial problems, and female sex were positively associated with depression whereas overall quality of life of caregiver, pre-loss grief, caregiver's education level, caregiver's age, caregiver's sense of coherence, and caregiver's bondage with patient were negatively associated with depression in caregivers.

conclusionA considerably high prevalence of depression is found in cancer patient caregivers. Several factors may affect depression and their quality of life of cancer patient caregivers.

Indexed as

AnxietyCaregiversDepressionFemaleHumansMaleNeoplasmsPrevalenceQuality of LifeRisk Factors

Identifiers

PMID30278483
PMCPMC6181540
OpenAlexW2894825479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.