ArticleEnvironment international2018
Environmental styrene exposure and neurologic symptoms in U.S. Gulf coast residents.
Article in Environment international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- Marine bacteria and fungi: the hidden treasure of oceans in the biodegradation of microplastics and hydrocarbons integrated with omics technologies.Archives of toxicology · 2026Review
- Blood concentrations of volatile organic compounds and hypertension in the GuLF Study.The Science of the total environment · 2025Article
- Associations between airborne crude oil chemicals and neurological symptoms among workers in the gulf long-term follow-up study.The Science of the total environment · 2025Article
- Concentrations of blood styrene and neurobehavioral function among Gulf state residents in the U.S.International journal of environmental health research · 2025Article
- A review of commercial plastic waste recycling into graphene materials.RSC advances · 2025Review
- Evaluation of Bayesian Maximum Entropy Data Fusion Approaches to Estimate Styrene, Benzene, Toluene, Ethylbenzene, and Xylenes and to Inform Epidemiological Analyses in the US Gulf States.Environmental science & technology · 2025Article
- Microplastics in aquatic systems: A comprehensive review of its distribution, environmental interactions, and health risks.Environmental science and pollution research international · 2025Review
- Article
- Evaluating the photocatalytic performance of MOF coated on glass for degradation of gaseous styrene under visible light.Scientific reports · 2024Article
- Air Quality Dispersion Modelling to Evaluate CIPP Installation Styrene Emissions.International journal of environmental research and public health · 2022Article
- ALS risk factors: Industrial airborne chemical releases.Environmental pollution (Barking, Essex : 1987) · 2022Article
- Chemistry, lung toxicity and mutagenicity of burn pit smoke-related particulate matter.Particle and fibre toxicology · 2021Article
- Blood BTEX levels and neurologic symptoms in Gulf states residents.Environmental research · 2019Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundStyrene is an established neurotoxicant at occupational levels, but effects at levels relevant to the general population have not been studied. We examined the neurologic effects of environmental styrene exposure among U.S. Gulf coast residents.
methodsWe used National Air Toxics Assessment (NATA) 2011 estimates of ambient styrene concentrations to assign exposure levels for 21,962 non-diabetic Gulf state residents, and additionally measured blood styrene concentration in a subset of participants (n = 874). Neurologic symptoms, as well as detailed covariate information, were ascertained via telephone interview. We used log-binomial regression to estimate prevalence ratios (PR) and 95% confidence intervals (95% CI) for cross-sectional associations between both ambient and blood styrene levels and self-reported neurologic symptoms. We estimated associations independently for ten unique symptoms, as well as for the presence of any neurologic, central nervous system (CNS), or peripheral nervous system (PNS) symptoms. We also examined heterogeneity of associations with estimated ambient styrene levels by race and sex.
resultsOne-third of participants reported at least one neurologic symptom. The highest quartile of estimated ambient styrene was associated with one or more neurologic (PR, 1.12; 95% CI: 1.07,1.18), CNS (PR, 1.17; 95% CI: 1.11,1.25), and PNS (PR, 1.16; 95% CI: 1.09,1.25) symptom. Results were less consistent for biomarker analyses, but blood styrene level was suggestively associated with nausea (PR, 1.78; 95% CI: 1.04, 3.03). In stratified analyses, we observed the strongest effects among non-White participants.
conclusionsIncreasing estimated ambient styrene concentration was consistently associated with increased prevalence of neurologic symptoms. Associations between blood styrene levels and some neurologic symptoms were suggestive. Environmental styrene exposure levels may be sufficient to elicit symptomatic neurotoxic effects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.