Evidence map›Paper›PMID 30278214›Full record

ArticleNeuroImage2019

Dual-calibrated fMRI measurement of absolute cerebral metabolic rate of oxygen consumption and effective oxygen diffusivity.

M Germuska, H L Chandler, R C Stickland, C Foster, F Fasano, T W Okell, J Steventon, V Tomassini, K Murphy, R G Wise

Abstract read
In one paragraph

Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Imaging effective oxygen diffusivity in the human brain with multiparametric magnetic resonance imaging.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Recent Advances in MR Imaging-based Quantification of Brain Oxygen Metabolism.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  10. Article
  11. Reduced brain oxygen metabolism in patients with multiple sclerosis: Evidence from dual-calibrated functional MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. A flow-diffusion model of oxygen transport for quantitative mapping of cerebral metabolic rate of oxygen (CMROJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  16. Review
  17. Hemodynamic and metabolic changes during hypercapnia with normoxia and hyperoxia using pCASL and TRUST MRI in healthy adults.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  18. Article
  19. Genotype-driven therapeutic developments in Parkinson's disease.Molecular medicine (Cambridge, Mass.) · 2021
    Review
  20. Hemodynamic impairments within individual watershed areas in asymptomatic carotid artery stenosis by multimodal MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M GermuskaCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK.
H L ChandlerCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK.
R C SticklandCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK.
C FosterCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK.
F FasanoSiemens Healthcare Ltd, Frimley, Camberley, UK.
T W OkellWellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.
J SteventonCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK.
V TomassiniDivision of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK; Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK.
K MurphyCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK.
R G WiseCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK. Electronic address: wiserg@cardiff.ac.uk.

Funding

Medical Research Council MC_PC_16041Medical Research Council MR/L010305/1Wellcome Trust 200804/Z/16/Z
6 · The paper itself

Abstract

Dual-calibrated fMRI is a multi-parametric technique that allows for the quantification of the resting oxygen extraction fraction (OEF), the absolute rate of cerebral metabolic oxygen consumption (CMRO

Indexed as

AdultBrainBrain MappingCerebrovascular CirculationDiffusionFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleModels, NeurologicalModels, TheoreticalOxygenOxygen ConsumptionPhotic StimulationOxygen

Identifiers

PMID30278214
PMCPMC6264385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.