Evidence map›Paper›PMID 30277572›Full record

ReviewCA: a cancer journal for clinicians2018

Improving patient and caregiver outcomes in oncology: Team-based, timely, and targeted palliative care.

David Hui, Breffni L Hannon, Camilla Zimmermann, Eduardo Bruera

2 registry-linked trialsOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CA: a cancer journal for clinicians, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 205 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
205citing papers in PubMed, 9 pooled it
30.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05190653 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Early Integration of Palliative and Supportive Care for Patients and Family Caregivers Undergoing Hematopoietic Stem Cell Transplantation or Chimeric Antigen Receptor T-Cell Therapy: A Prospective Pragmatic Randomized Clinical Trial

TypeinterventionalSponsorAlberta Health Services, CalgaryRan2022 to 2025Enrolled152ConditionsLeukemia, Lymphoma, Multiple Myeloma, Blood CancerArmsEarly palliative and supportive care
NCT07554209 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Perceptions Among Healthcare Professionals of Key Domains of Home-Based Palliative Care: A Multicriteria Comparative Cross-Sectional Survey (MULTIPAL)

TypeobservationalSponsorInstituto de Investigacion Sanitaria La FeRan2026 to 2026Enrolled580ConditionsHome Care, Hospital-Based, Palliative Care, Health Services Research, Decision Making
3 · Its place in the literature

Who cites it

205 citing papers in PubMed, 9 syntheses or guidelines pooled it, 430 citations in OpenAlex.

  1. A systematic review of the assessment model for palliative care needs in cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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  3. Application of virtual reality for supportive care in cancer patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  14. Symptom screening with Targeted Early Palliative care (STEP) versus usual care for patients with advanced cancer: a mixed methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  19. Timing and outcomes of outpatient palliative care consultations in advanced cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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145 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

David HuiDepartment of Palliative Care, Rehabilitation, and Integrative Medicine and Department of General Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Breffni L HannonDepartment of Supportive Care, Princess Margaret Cancer Center, University Health Network, University of Toronto, Toronto, ON, Canada.
Camilla ZimmermannDepartment of Supportive Care, Princess Margaret Cancer Center, University Health Network, University of Toronto, Toronto, ON, Canada.
Eduardo BrueraDepartment of Palliative Care, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.
The University of Texas MD Anderson Cancer Center · USPrincess Margaret Cancer Centre · CAUniversity Health Network · CA

Funding

A Randomized Controlled Trial of Dexamethasone for Dyspnea in Cancer PatientsR01CA214960 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2017 to 2020
$1.6M
Palliative Therapies for Refractory Delirium in Advanced CancerR21NR016736 · NINR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2017 to 2018
$455k
CIHR 152996NCI NIH HHS R01 CA214960NINR NIH HHS R21 NR016736
6 · The paper itself

Abstract

Over the past decade, a large body of evidence has accumulated supporting the integration of palliative care into oncology practice for patients with advanced cancer. The question is no longer whether palliative care should be offered, but what is the optimal model of delivery, when is the ideal time to refer, who is in greatest need of a referral, and how much palliative care should oncologists themselves be providing. These questions are particularly relevant given the scarcity of palliative care resources internationally. In this state-of-the-science review directed at the practicing cancer clinician, the authors first discuss the contemporary literature examining the impact of specialist palliative care on various health outcomes. Then, conceptual models are provided to support team-based, timely, and targeted palliative care. Team-based palliative care allows the interdisciplinary members to address comprehensively the multidimensional care needs of patients and their caregivers. Timely palliative care, at its best, is preventive care to minimize crises at the end of life. Targeted palliative care involves identifying the patients most likely to benefit from specialist palliative care interventions, akin to the concept of targeted cancer therapies. Finally, the strengths and weaknesses of innovative care models, such as outpatient clinics, embedded clinics, nurse-led palliative care, primary palliative care provided by oncology teams, and automatic referral, are summarized. Moving forward, more research is needed to determine how different health systems can best personalize palliative care to provide the right level of intervention, for the right patient, in the right setting, at the right time. CA Cancer J Clin. 2018;680:00-00. 2018 American Cancer Society, Inc.

Indexed as

CaregiversPatient Care TeamAmbulatory CareDelivery of Health CareEvidence-Based MedicineHumansNeoplasmsOncologistsPalliative CarePhysician's RoleQuality of LifeReferral and ConsultationTime-to-Treatmentaccessdelivery of health careintegrationneoplasmspalliative care

Identifiers

PMID30277572
PMCPMC6179926
OpenAlexW2891258991

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.