Evidence map›Paper›PMID 30277458›Full record

ArticleeLife2018

Rif1 inhibits replication fork progression and controls DNA copy number in Drosophila.

Alexander Munden, Zhan Rong, Amanda Sun, Rama Gangula, Simon Mallal, Jared T Nordman

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. eLife · 2022
    Article
  10. Article
  11. DNA replication timing: Biochemical mechanisms and biological significance.BioEssays : news and reviews in molecular, cellular and developmental biology · 2022
    Article
  12. Article
  13. Article
  14. Temporal control of late replication and coordination of origin firing by self-stabilizing Rif1-PP1 hubs inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexander MundenDepartment of Biological Sciences, Vanderbilt University, Nashville, United States.
Zhan RongDepartment of Biological Sciences, Vanderbilt University, Nashville, United States.
Amanda SunDepartment of Biological Sciences, Vanderbilt University, Nashville, United States.
Rama GangulaDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, United States.
Simon MallalDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, United States.
Jared T NordmanDepartment of Biological Sciences, Vanderbilt University, Nashville, United States.ORCID http://orcid.org/0000-0002-6612-3201
Vanderbilt University · US

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephany Norah Duda · 2015 to 2026
$27.5M
Developmental control of replication initiation and genome stabilityR35GM128650 · NIGMS · VANDERBILT UNIVERSITY · PI Jared Nordman · 2018 to 2026
$3.3M
Regulation of metazoan DNA replication fork progression, stability and compositioR00GM104151 · NIGMS · VANDERBILT UNIVERSITY · PI NORDMAN, JARED · 2015 to 2017
$737k
High-Performance Computer Cluster for Biomedical ResearchS10OD023680 · OD · VANDERBILT UNIVERSITY · PI MEILER, JENS · 2017 to 2017
$587k
NIAID NIH HHS P30 AI110527NIGMS NIH HHS R00 GM104151NIGMS NIH HHS R35 GM128650NIH HHS 5R00GM104151NIH HHS P30 AI110527NIH HHS S10 OD023680
6 · The paper itself

Abstract

Control of DNA copy number is essential to maintain genome stability and ensure proper cell and tissue function. In

Indexed as

DNA ReplicationGene DosageAmino Acid SequenceAnimalsCarrier ProteinsDNADNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsGenome, InsectHeat-Shock ResponseHeterochromatinMutationProtein BindingProtein DomainsReproducibility of ResultsCarrier ProteinsDNADNA-Binding ProteinsDrosophila ProteinsHeterochromatinRif1 protein, DrosophilaSuUR protein, Drosophilachromosomescommon fragile sitesdevelopmental biologyD. melanogasterDNA replicationgene expressiongenome stabilitypolyploidreplication timingunder replication

Identifiers

PMID30277458
PMCPMC6185109
OpenAlexW2950898487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.