Evidence map›Paper›PMID 30277315›Full record

ArticleMicrobiologyOpen2019

Cryptococcal antigenemia and associated risk factors among ART-naïve and ART-experienced HIV-infected peoples at selected health institutions of Mekelle, Northern Ethiopia.

Kibra Hailu, Selam Niguse, Kiflom Hagos, Mahmud Abdulkader

Open access · goldAbstract read
In one paragraph

Article in MicrobiologyOpen, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Invasive Fungal Diseases in Africa: A Critical Literature Review.Journal of fungi (Basel, Switzerland) · 2022
    Article
  6. Observational
  7. Review
  8. Opportunistic Cryptococcal Antigenemia in the HAART Era at HIV Epidemic Settings of Northwest Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kibra HailuLaboratory Department, Ayder Comprehensive Specialized Hospital, Mekelle, Ethiopia.
Selam NiguseMedical Microbiology and Immunology Unit, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.ORCID 0000-0002-4732-9546
Kiflom HagosMedical Microbiology and Immunology Unit, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Mahmud AbdulkaderMedical Microbiology and Immunology Unit, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Mekelle University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcal infection is a major cause of opportunistic infection in HIV/AID-infected peoples. We determined cryptococcal antigenemia and cryptococcal meningitis among antiretroviral therapy (ART) initiated and ART-naive HIV-infected peoples. A cross-sectional study was conducted at selected health facilities in Mekelle, Ethiopia. Blood was collected to determine CD4 and plasma cryptococcal antigen (CrAg). CSF CrAg and CSF culture and urease tests were also done. Socio-demographic and clinical data were collected using a structured questionnaire and clinical chart review. From the enrolled study participants, 267 study participants had complete data, of which, 137 (51%) were females. From the study participants, 140 (52%) and 127 (48%) were ART experienced and ART naïve, respectively. The prevalence of cryptococcal antigenemia was 9 (3.4%). All the study participants, except one (CD4 = 120 cells/mm

Indexed as

AdultAIDS-Related Opportunistic InfectionsAntigens, FungalAnti-HIV AgentsCD4 Lymphocyte CountCross-Sectional StudiesCryptococcosisCryptococcusEthiopiaFemaleHIV InfectionsHumansMaleMiddle AgedYoung AdultAntigens, FungalAnti-HIV AgentsART-experiencedART-naivecryptococcal antigenemiaHIV infectedMekelle

Identifiers

PMID30277315
PMCPMC6562113
OpenAlexW2895764037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.