Evidence map›Paper›PMID 30277270›Full record

ArticleMagnetic resonance in medicine2019

Machine learning improves classification of preclinical models of pancreatic cancer with chemical exchange saturation transfer MRI.

Joshua M Goldenberg, Julio Cárdenas-Rodríguez, Mark D Pagel

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joshua M GoldenbergDepartment of Pharmaceutical Sciences, University of Arizona, Tucson, Arizona.
Julio Cárdenas-RodríguezBanner University Medical Center, University of Arizona, Tucson, Arizona.
Mark D PagelDepartment of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, Texas.

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
SPORE in Gastrointestinal CancerP50CA095060 · NCI · UNIVERSITY OF ARIZONA · PI GERNER, EUGENE W · 2002 to 2012
$25.3M
Detection of in vivo enzyme activities with CEST MRIR01CA169774 · NCI · UNIVERSITY OF ARIZONA · PI CARDENAS-RODRIGUEZ, JULIO · 2012 to 2016
$2.5M
Measuring extracellular pH in pre-clinical tumor models with CEST MRIR01CA167183 · NCI · UNIVERSITY OF ARIZONA · PI PAGEL, MARK DAVID · 2012 to 2015
$1.6M
Institutional Research 128749-IRG-16-124-37-IRGNCI NIH HHS P30 CA023074NCI NIH HHS P50 CA095060NCI NIH HHS R01 CA167183NCI NIH HHS R01 CA169774NIH HHS P30CA023074NIH HHS P50CA95060NIH HHS R01CA169774the National Natural Science Foundation of China 31360442
6 · The paper itself

Abstract

purposeWe sought to assess whether machine learning-based classification approaches can improve the classification of pancreatic tumor models relative to more simplistic analysis methods, using T

methodsThe T

resultsThe T

conclusionsMachine learning applied to the entire CEST spectrum improved the classification of the three tumor models, relative to classifications that used % CEST values at single saturation frequencies. A similar improvement was not attained with machine learning applied to T

Indexed as

Machine LearningMagnetic Resonance ImagingAlgorithmsAnimalsArea Under CurveCell Line, TumorFemaleHumansHypoxiaImage EnhancementImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMiceMice, SCIDNormal DistributionPancreatic NeoplasmsCESTDCE. machine learningMRIpancreatic cancer imagingPCA

Identifiers

PMID30277270
PMCPMC6258293

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.