Evidence map›Paper›PMID 30277201›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Case Report: Acute Transverse Myelitis after Zika Virus Infection.

Vanderson Carvalho Neri, Maria Filomena Xavier, Priscila Oliveira Barros, Cleonice Melo Bento, Romain Marignier, Regina Papais Alvarenga

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Zika virus infection and acute transverse myelitis: a comprehensive systematic review.Revista do Instituto de Medicina Tropical de Sao Paulo · 2024
    Pooled it
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  16. Nervous System Manifestations of Arboviral Infections.Current tropical medicine reports · 2022
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  18. Immune-Mediated Disorders Affecting the Spinal Cord and the Spine.Current neurology and neuroscience reports · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Vanderson Carvalho NeriNeurology Department, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Maria Filomena XavierMultiple Sclerosis Treatment Center, Hospital Federal da Lagoa, Rio de Janeiro, Brazil.
Priscila Oliveira BarrosDepartment of Microbiology and Parasitology, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Cleonice Melo BentoDepartment of Microbiology and Parasitology, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Romain MarignierUniversiteì Lyon 1, Universiteì de Lyon, Lyon, France.
Regina Papais AlvarengaMultiple Sclerosis Treatment Center, Hospital Federal da Lagoa, Rio de Janeiro, Brazil.
Universidade Federal do Estado do Rio de Janeiro · BRHospices Civils de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here one case of Zika virus (ZIKV) infection associated with auto-immunity directed against the central nervous system in a Brazilian woman who developed acute transverse myelitis 9 days after recovery from an acute episode of fever with generalized erythema. Imaging of the spinal cord showed an elongated area on the T1-T10 level with gadolinium uptake. The diagnostic of the ZIKV infection was confirmed by cerebrospinal fluid and serum analysis. This patient had serum positivity for autoantibodies against myelin oligodendrocyte glycoprotein (MOG), a specific antibody against the myelin sheath. We propose that a direct central nervous system infection by ZIKV could lead to a specific auto-immunity against MOG protein.

Indexed as

Acute DiseaseAdultAutoantibodiesBrazilContrast MediaErythemaFemaleGadoliniumHumansMagnetic Resonance ImagingMyelin-Oligodendrocyte GlycoproteinMyelin SheathMyelitis, TransverseSpinal CordZika VirusZika Virus InfectionAutoantibodiesContrast MediaGadoliniumMOG protein, humanMyelin-Oligodendrocyte Glycoprotein

Identifiers

PMID30277201
PMCPMC6283478
OpenAlexW2894955744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.