Evidence map›Paper›PMID 30276807›Full record

ReviewJournal of neurochemistry2019

Epigenetic cues modulating the generation of cell-type diversity in the cerebral cortex.

Nicole Amberg, Susanne Laukoter, Simon Hippenmeyer

Abstract readReview
In one paragraph

Review in Journal of neurochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Shaping the Neocortex: Radial Glia and Astrocytes in Development and Evolution.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Transcriptional network orchestrating regional patterning of cortical progenitors.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Matrix Metalloproteinase-9 Gene Polymorphism and Its Methylation in Stroke Patients.The Malaysian journal of medical sciences : MJMS · 2021
    Article
  9. Article
  10. Observational
  11. Chromatin Remodeling in the Brain-aInternational journal of molecular sciences · 2021
    Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicole AmbergInstitute of Science and Technology Austria, Klosterneuburg, Austria.
Susanne LaukoterInstitute of Science and Technology Austria, Klosterneuburg, Austria.
Simon HippenmeyerInstitute of Science and Technology Austria, Klosterneuburg, Austria.ORCID 0000-0003-2279-1061

Funding

Austrian Science Fund FWF T 1031
6 · The paper itself

Abstract

The cerebral cortex is composed of a large variety of distinct cell-types including projection neurons, interneurons, and glial cells which emerge from distinct neural stem cell lineages. The vast majority of cortical projection neurons and certain classes of glial cells are generated by radial glial progenitor cells in a highly orchestrated manner. Recent studies employing single cell analysis and clonal lineage tracing suggest that neural stem cell and radial glial progenitor lineage progression are regulated in a profound deterministic manner. In this review we focus on recent advances based mainly on correlative phenotypic data emerging from functional genetic studies in mice. We establish hypotheses to test in future research and outline a conceptual framework how epigenetic cues modulate the generation of cell-type diversity during cortical development.

Indexed as

AnimalsCell DifferentiationCerebral CortexEpigenesis, GeneticHumansNeural Stem CellsNeurogenesiscell-type diversitycerebral cortexgliogenesislineage progressionneurogenesisradial glial progenitor cells

Identifiers

PMID30276807
PMCPMC6587822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.