Evidence map›Paper›PMID 30276684›Full record

ArticleEnvironmental science and pollution research international2018

Protective potential of Opuntia microdasys flower decoction on fructose-alloxan-induced diabetic rats on kidney and pancreas: chemical and immunohistochemical analyses.

Hassiba Chahdoura, Aida Khlifi, Jihéne Ben Lamine, Borhane Eddine Cherif Ziani, Khawla Adouni, Safia El Bok, Zohra Haouas, Fadoua Neffati, Abdelfattah Zakhama, Guido Flamini and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Hassiba ChahdouraLaboratoire de Recherche "Bioressourses, Biologie Intégrative and Valorisation," Institut Supérieur de Biotechnologie de Monastir, Université de Monastir, Avenue Tahar Hadded, BP 74, 5000, Monastir, Tunisia. hassiba_chahdoura@yahoo.fr.
Aida KhlifiLaboratoire de Recherche "Bioressourses, Biologie Intégrative and Valorisation," Institut Supérieur de Biotechnologie de Monastir, Université de Monastir, Avenue Tahar Hadded, BP 74, 5000, Monastir, Tunisia.
Jihéne Ben LamineLaboratoire de Recherche "Bioressourses, Biologie Intégrative and Valorisation," Institut Supérieur de Biotechnologie de Monastir, Université de Monastir, Avenue Tahar Hadded, BP 74, 5000, Monastir, Tunisia.
Borhane Eddine Cherif ZianiCentre de recherche scientifique et Technique en Analyses physico-chimiques CRAPC, Bouismail, Tipaza, Algeria.
Khawla AdouniLaboratoire de Recherche "Bioressourses, Biologie Intégrative and Valorisation," Institut Supérieur de Biotechnologie de Monastir, Université de Monastir, Avenue Tahar Hadded, BP 74, 5000, Monastir, Tunisia.
Safia El BokLaboratoire de Biodiversité, Biotechnologies et Changements Climatiques, Faculté des Sciences de Tunis, Université Tunis-El Manar, Tunis, Tunisia.
Zohra HaouasLaboratory of Histology and Cytogenetic, Faculty of Medicine, Monastir, Tunisia.
Fadoua NeffatiLaboratoire de Biochimie, Hôpital Universitaire de Monastir, Monastir, Tunisia.
Abdelfattah ZakhamaService of Pathological Anatomy CHU F. Bourguiba, Monastir, Tunisia.
Guido FlaminiDipartimento di Farmacia, Via Bonanno 6, 56126, Pisa, Italy.
Lotfi AchourLaboratoire de Recherche "Bioressourses, Biologie Intégrative and Valorisation," Institut Supérieur de Biotechnologie de Monastir, Université de Monastir, Avenue Tahar Hadded, BP 74, 5000, Monastir, Tunisia.
University of Monastir · TNCentre de Recherche sur l'Information Scientifique et Technique · DZHospital Fatuma Bourguiba Monastir · TNTunis El Manar University · TNUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes is a serious condition that is linked to the development of oxidative stress causing among many other effects, kidney failure and pancreatic disorders. However, traditional plant-based remedies can be considered an alternative to diabetes healing. In this context, this study was oriented towards evaluating the protective effect of the flowers of Opuntia microdasys Lehm. collected in Tunisia at a biochemical and histological level on kidneys and pancreas of a type 2 diabetic rats. Renal and pancreatic toxicities were induced in diabetic male Wistar rats by fructose alloxan. Diabetic rats were treated with an extract obtained from flowers collected at post-flowering stage (OFP) (100 and 200 mg kg

Indexed as

AlloxanAnimalsBlood GlucoseDiabetes Mellitus, ExperimentalFlowersFructoseHypoglycemic AgentsKidneyLipid PeroxidationMaleOpuntiaOxidative StressPancreasPlant ExtractsRats, WistarThiobarbituric Acid Reactive SubstancesAlloxanBlood GlucoseFructoseHypoglycemic AgentsPlant ExtractsThiobarbituric Acid Reactive SubstancesAntioxidant systemDiabetesHistopathologyImmunohistologyOpuntia microdasys LehmRenal and pancreatic markers

Identifiers

PMID30276684
OpenAlexW2895259233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.