Evidence map›Paper›PMID 30276676›Full record

ArticleEuropean radiology2019

Microvascular characteristics of lower-grade diffuse gliomas: investigating vessel size imaging for differentiating grades and subtypes.

Hong Guo, Houyi Kang, Haipeng Tong, Xuesong Du, Heng Liu, Yong Tan, Yizeng Yang, Sumei Wang, Weiguo Zhang

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Hong GuoDepartment of Radiology, Institute of Surgery Research, Daping Hospital, Army Medical University, 10# Changjiang Branch Road, Chongqing, People's Republic of China, 400024.
Houyi KangDepartment of Radiology, Institute of Surgery Research, Daping Hospital, Army Medical University, 10# Changjiang Branch Road, Chongqing, People's Republic of China, 400024.
Haipeng TongDepartment of Radiology, Institute of Surgery Research, Daping Hospital, Army Medical University, 10# Changjiang Branch Road, Chongqing, People's Republic of China, 400024.
Xuesong DuDepartment of Radiology, Institute of Surgery Research, Daping Hospital, Army Medical University, 10# Changjiang Branch Road, Chongqing, People's Republic of China, 400024.
Heng LiuDepartment of Radiology, Institute of Surgery Research, Daping Hospital, Army Medical University, 10# Changjiang Branch Road, Chongqing, People's Republic of China, 400024.
Yong TanDepartment of Radiology, Institute of Surgery Research, Daping Hospital, Army Medical University, 10# Changjiang Branch Road, Chongqing, People's Republic of China, 400024.
Yizeng YangDepartment of Medicine, Gastroenterology Division, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
Sumei WangDepartment of Radiology, Division of Neuroradiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA.
Weiguo ZhangDepartment of Radiology, Institute of Surgery Research, Daping Hospital, Army Medical University, 10# Changjiang Branch Road, Chongqing, People's Republic of China, 400024. wgzhang01@163.com.
Daping Hospital · CNArmy Medical University · CNHospital of the University of Pennsylvania · USUniversity of Pennsylvania · US

Funding

Clinical Scientific Foundation of Institute of Surgery Research, Daping Hospital, Third Military Medical University 2014YLC03International Collaboration of Technological Research Program of Chongqing cstc2014gjhz110002the National Natural Science Foundation of China (NSFC) 81571660
6 · The paper itself

Abstract

objectivesVessel size imaging (VSI) could reveal average microvessel diameter. The aim was to investigate microvascular characteristics and the efficacy of VSI in lower-grade glioma (LGG) grading and subtype differentiation based on 2016 classification of central nervous system tumours.

methodsFifty-seven LGG (grade II/III, 36/21) patients who received VSI examination before surgery were retrospectively analysed. The average (R

resultsR

conclusionsVSI holds great potential for non-invasively revealing microvascular characteristics of LGGs pre-surgery and differentiating their grades and molecular subtypes. KEY POINTS: • VSI can assist in differentiating grade-II and -III gliomas. • The IDH gene and 1p/19q chromosome may influence the angiogenesis in grade-II gliomas. • VSI is valuable for differentiating the molecular subtypes of grade-II gliomas.

Indexed as

MicrocirculationAdultAstrocytomaBrain NeoplasmsChromosome DeletionFemaleGliomaHumansIsocitrate DehydrogenaseMagnetic Resonance ImagingMaleMiddle AgedMutationOligodendrogliomaRetrospective StudiesIsocitrate DehydrogenaseGliomaMicrovesselsMolecular typingVessel size imaging

Identifiers

PMID30276676
PMCPMC6420610
OpenAlexW2895353541

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.