ArticleEuropean radiology2019
Quantitative susceptibility mapping in the human fetus to measure blood oxygenation in the superior sagittal sinus.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Diminished Cerebral Oxygen Extraction and Metabolic Rate in Neonates With Hypoxic Ischemic Encephalopathy.Stroke · 2025Article
- Advancements in MRI application in the morphological development of fetal cerebral venous system: a review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Review
- In vivo mapping of hippocampal venous vasculature and oxygenation using susceptibility imaging at 7T.NeuroImage · 2024Article
- Fetal MRI: what's new? A short review.European radiology experimental · 2023Review
- Cerebral oxygen metabolism from MRI susceptibility.NeuroImage · 2023Review
- QSM Throughout the Body.Journal of magnetic resonance imaging : JMRI · 2023Review
- Cerebral oxygen extraction fraction MRI: Techniques and applications.Magnetic resonance in medicine · 2022Review
- Methods for Monitoring Risk of Hypoxic Damage in Fetal and Neonatal Brains: A Review.Fetal diagnosis and therapy · 2022Review
- Photoacoustic assessment of the fetal brain and placenta as a method of non-invasive antepartum and intrapartum monitoring.Experimental neurology · 2022Review
- White matter abnormalities and iron deposition in prenatal mucolipidosis IV- fetal imaging and pathology.Metabolic brain disease · 2021Article
- Quantitative Susceptibility Mapping of Venous Vessels in Neonates with Perinatal Asphyxia.AJNR. American journal of neuroradiology · 2021Article
- The application ofJournal of developmental origins of health and disease · 2021Review
- Development of Brain Networks In Utero: Relevance for Common Neural Disorders.Biological psychiatry · 2020Review
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
Abstract
objectivesTo present the feasibility of performing quantitative susceptibility mapping (QSM) in the human fetus to evaluate the oxygenation (S
methodsSusceptibility weighted imaging (SWI) data were acquired from healthy pregnant subjects (n = 21, median = 31.3 weeks, interquartile range = 8.8 weeks). The susceptibility maps were generated from the SWI-phase images using a modified QSM processing pipeline, optimised for fetal applications. The processing pipeline is as follows: (1) mild high-pass filtering followed by quadratic fitting of the phase images to eliminate background phase variations; (2) manual creation of a fetal brain mask that includes the superior sagittal sinus (SSS); (3) inverse filtering of the resultant masked phase images using a truncated k-space approach with geometric constraint. Further, the magnetic susceptibility, ∆χ
resultsSimulations showed that the systematic error in S
conclusionsThis in vivo study demonstrates the feasibility of using QSM in the human fetal brain to estimate ∆χ KEY POINTS: • A modified quantitative susceptibility mapping (QSM) processing pipeline is tested and presented for the human fetus. • QSM is feasible in the human fetus for measuring magnetic susceptibility and oxygenation of venous blood in vivo. • Blood magnetic susceptibility values from MR susceptometry and QSM agree with each other in the human fetus.
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