Evidence map›Paper›PMID 30276665›Full record

ArticleAnatomical science international2019

Cochlear hair cell densities in the rabbit.

Fang Yuan, Dalian Ding, Yitan Cao, Weidong Qi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anatomical science international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Fang YuanDepartment of Otolaryngology Head and Neck Surgery, Huashan Hospital Fudan University, 200040, Shanghai, China.
Dalian DingDepartment of Communicative Disorders and Sciences, Center for Hearing and Deafness, State University of New York at Buffalo, New York, Buffalo, 14214, USA.
Yitan CaoDepartment of Otolaryngology Head and Neck Surgery, Huashan Hospital Fudan University, 200040, Shanghai, China.
Weidong QiDepartment of Otolaryngology Head and Neck Surgery, Huashan Hospital Fudan University, 200040, Shanghai, China. drqiweidong@126.com.
Fudan University · CNHuashan Hospital · CNUniversity at Buffalo, State University of New York · US

Funding

Science and Technology Commission of Shanghai Municipality 15140900900
6 · The paper itself

Abstract

A typical cochleogram was plotted to investigate hair cell densities as a percentage along the whole length of the basilar membrane (BM) of the rabbit, the length of the BM and the width of the organ of Corti. We generated surface preparations of cochlea from adult, healthy New Zealand White (NZW) rabbits. The numbers of inner hair cells (IHCs) and outer hair cells (OHCs) were counted from images acquired from a digital camera attached to an Olympus light microscope with a scale of 100 μm as a primary unit drawn continuously, and the numbers of IHCs and OHCs were converted to densities at 10% intervals along the length of the cochlea. Meanwhile, the length of the BM and the width of the organ of Corti were calculated. The average length of the cochlea was 14.504 ± 0.403 mm, while the total number of IHCs and the numbers of OHCs in the first, second, and third rows were 1556 ± 13, 1840 ± 47, 1842 ± 46, and 1840 ± 45, respectively, accounting for 21.98%, 26.00%, 26.02%, and 26.00% of the total number of cells, respectively. The densities of each row of OHCs reported in 10% intervals were greater than the densities of the IHCs corresponding to their anatomical locations within the cochlea. The densities of OHCs in each row were distributed uniformly along the BM, while the IHCs densities were not and showed a bimodal distribution with a maximum density at the apex and at 70-80% of the cochlear length from the apex but a lower density in the remaining cochlea. The width of the organ of Corti decreased successively from the apex to the base.

Indexed as

Hair Cells, Auditory, InnerHair Cells, Auditory, OuterAnimalsCell CountImage Processing, Computer-AssistedMicroscopyModels, AnimalRabbitsSoftwareCochleogramHair cellQuantitative analysisRabbit

Identifiers

PMID30276665
PMCPMC6314996
OpenAlexW2895003738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.