Observational studyInternal and emergency medicine2019
Red cell distribution width predicts mid-term prognosis in patients hospitalized with acute heart failure: the RDW in Acute Heart Failure (RE-AHF) study.
Observational study in Internal and emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 48 citations in OpenAlex.
- Elevated Red Blood Cell Distribution Width Predicts Mortality and Major Adverse Cardiovascular Events After Acute Myocardial Infarction: A Large Propensity Score-Matched Cohort Study.Journal of clinical medicine · 2026Article
- High red cell distribution width as a prognostic indicator in heart failure.World journal of methodology · 2026Article
- Red blood cell distribution width/albumin ratio (RAR): A novel predictor of retinal vein occlusion in the Turkish population (STROBE).Medicine · 2026Article
- Article
- Prognostic Value of the Red Cell Distribution Width-to-eGFR Ratio (RGR) Across Chronic Heart Failure Phenotypes: A Retrospective Observational Pilot Study.Journal of clinical medicine · 2025Article
- Association between red cell distribution width-to-lymphocyte ratio and 30-day mortality in patients with ischemic stroke: a retrospective cohort study.Thrombosis journal · 2024Article
- The red blood cell distribution width to albumin ratio was a potential prognostic biomarker for acute respiratory failure: a retrospective study.BMC medical informatics and decision making · 2024Article
- Article
- Association between red cell distribution width and 30-day mortality in patients with sepsis-associated liver injury: a retrospective cohort study.Frontiers in medicine · 2024Article
- The long-term impact of increased red blood cell distribution width detected during hospitalization for heart failure.Biomarkers in medicine · 2024Article
- In-hospital changes in the red blood cell distribution width and mortality in critically ill patients with heart failure.ESC heart failure · 2023Article
- Interpretable prediction of 3-year all-cause mortality in patients with chronic heart failure based on machine learning.BMC medical informatics and decision making · 2023Article
- Predictive nomogram for in-hospital mortality among older patients with intra-abdominal sepsis incorporating skeletal muscle mass.Aging clinical and experimental research · 2023Article
- Red blood cell distribution width and Charlson comorbidity index help to identify frail polytraumatized patients : Experiences from a level I trauma center.Wiener klinische Wochenschrift · 2023Article
- Red blood cell distribution width improves the prediction of 28-day mortality for patients with sepsis-induced acute kidney injury: A retrospective analysis from MIMIC-IV database using propensity score matching.Journal of intensive medicine · 2023Article
- Red cell distribution width as a prognosticator in patients with heart failure.ESC heart failure · 2023Article
- One-year rehospitalisation and mortality after acute heart failure hospitalisation: a competing risk analysis.Open heart · 2023Observational
- Association of red cell distribution width with the risk of 3-month readmission in patients with heart failure: A retrospective cohort study.Frontiers in cardiovascular medicine · 2023Article
- Red blood cell distribution width and all-cause mortality in congestive heart failure patients: a retrospective cohort study based on the Mimic-III database.Frontiers in cardiovascular medicine · 2023Article
- Comparison of the red blood cell indices based on accuracy, sensitivity, and specificity to predict one-year mortality in heart failure patients.BMC cardiovascular disorders · 2022Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to evaluate the prognostic role of red cell distribution width (RDW) in a broad population of patients hospitalized for acute heart failure (AHF). In a retrospective cohort observational study, 451 consecutive patients discharged for AHF were categorized in patients with low RDW (≤ 14.8%) and high RDW (> 14.8%). The rates of death from all causes or of hospital readmission for worsening heart failure and death were determined after a median follow-up of 18 months. The overall population has a median age of 80 years (IQR 72-85), 235 patients (52%) were males. Patients with a higher RDW have more comorbidities and a higher Charlson Index. At follow-up, 200 patients (44%) had died and 247 (54%) had died or were readmitted for HF: in the cohort with low RDW, 70 patients (36.4%) had died, whereas in the cohort with high RDW, 165 patients (63.7%) had died: the unadjusted risk ratio of patients with high RDW was 2.03 (log-rank test: p < 0.0001). In a multivariate Cox regression model, the hazard ratio for death from any cause in the 'high RDW' cohort is 1.73 (95% confidence interval 1.2-2.48; p = 0.003); the RDW adds prognostic information beyond that provided by conventional predictors, including age; etiology of HF; anemia; hyponatremia; estimated glomerular filtration rate; NT-proBNP levels; Charlson comorbidity score, atrial fibrillation, functional status, therapy with renin-angiotensin-aldosterone system inhibitors, beta-blockers. RDW is a powerful marker of worse long-term outcomes in patients with AHF, and its prognostic value is maintained beyond that provided by other well-established risk factors or biomarkers.
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