ArticleAnnals of nuclear medicine2019
Count-based method for specific binding ratio calculation in [I-123]FP-CIT SPECT analysis.
Article in Annals of nuclear medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- SPECT hybrid approach combining conventional and deep features for early detection of Parkinson's disease.Physical and engineering sciences in medicine · 2026Article
- The effects of use of medications on striatal dopamine transporter binding assessed by [European journal of nuclear medicine and molecular imaging · 2026Article
- TMS-evoked potentials unveil occipital network involvement in patients diagnosed with Parkinson's disease within 5 years of inclusion.NPJ Parkinson's disease · 2024Article
- Specific Binding Ratio Estimation of [Diagnostics (Basel, Switzerland) · 2023Article
- A new quantitative index in the diagnosis of Parkinson syndrome by dopamine transporter single-photon emission computed tomography.Annals of nuclear medicine · 2021Article
- A Novel Automatic Approach for Calculation of the Specific Binding Ratio in [I-123]FP-CIT SPECT.Diagnostics (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo calculate the specific binding ratio (SBR) appropriately in dopamine transporter (DAT) imaging, a method for extracting the striatal volume of interest (VOI) was developed.
methodsThis study included 200 patients (72 ± 10 years) who were suspected of parkinsonian syndromes (PS) or dementia with Lewy body (DLB). The patients were divided into three groups of PS with dopaminergic degeneration, DLB and non-PS after [
resultsThe mean SBR values for the PS and DLB groups were significantly different from that of the non-PS group with both methods. The coefficients of variation of the SBR were significantly smaller with the proposed method compared with those of SBR
conclusionOur new method for SBR calculation in the FP-CIT SPECT showed less coefficients of variation with high reproducibility, which would be useful for clinical diagnosis and in assessing the severity of diseases in follow-up studies.
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