Evidence map›Paper›PMID 30276571›Full record

ReviewDigestive diseases and sciences2018

Utility of Esophageal High-Resolution Manometry in Clinical Practice: First, Do HRM.

Ishita Dhawan, Brendon O'Connell, Amit Patel, Ron Schey, Henry P Parkman, Frank Friedenberg

Abstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Guideline
  2. Future perspectives in esophageal manometry.World journal of gastrointestinal surgery · 2025
    Review
  3. Article
  4. Optimizing achalasia diagnosis in the era of high-resolution manometry: A Pakistani perspective.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  5. Article
  6. Review
  7. Esophageal Motility Patterns in Paraesophageal Hernia Patients Compared to Sliding Hiatal Hernia: Bigger Is Not Better.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  8. Review
  9. Patterns of esophageal dysmotility elicited by multiple rapid swallows.Esophagus : official journal of the Japan Esophageal Society · 2021
    Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ishita DhawanDepartment of Medicine, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, PA, USA.
Brendon O'ConnellDivision of Gastroenterology, Durham Veterans Affairs Medical Center, Duke University School of Medicine, Durham, USA.
Amit PatelDivision of Gastroenterology, Durham Veterans Affairs Medical Center, Duke University School of Medicine, Durham, USA.
Ron ScheyGastroenterology Section, Department of Medicine, Lewis Katz School of Medicine, Temple University School of Medicine, Philadelphia, PA, USA.
Henry P ParkmanGastroenterology Section, Department of Medicine, Lewis Katz School of Medicine, Temple University School of Medicine, Philadelphia, PA, USA.
Frank FriedenbergGastroenterology Section, Department of Medicine, Lewis Katz School of Medicine, Temple University School of Medicine, Philadelphia, PA, USA. frank.friedenberg@tuhs.temple.edu.
Temple University · USDuke University · USUniversity of Pennsylvania Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal high-resolution manometry (HRM) has advanced the understanding of esophageal motor function and the ability to diagnose and manage disorders of esophageal motility. In this review, we describe the indications for and the technical performance of HRM. The Chicago classification of esophageal motor function, now in its third iteration, streamlines and standardizes the nomenclature and basic interpretation of HRM data depicted as Clouse topographic plots. In clinical practice, HRM is an important diagnostic test for patients with dysphagia as well as patients with suspected gastroesophageal reflux disease (GERD), particularly in those patients with a suboptimal symptomatic response to antisecretory therapy. HRM can support diagnoses such as achalasia, as well as provide evidence for behavioral disorders such as rumination syndrome or supragastric belching with the assistance of postprandial HRM with impedance. Further, the GERD classification of motor function introduces a three-part hierarchical evaluation of esophageal motor function in GERD, highlighting the value of assessment of esophageal contractile reserve through provocative maneuvers during HRM such as multiple rapid swallows.

Indexed as

Esophageal Motility DisordersEsophagusHumansManometryAntireflux surgery (ARS)Chicago classificationEsophageal high-resolution manometry (HRM)Gastroesophageal reflux disease (GERD)

Identifiers

PMID30276571
OpenAlexW2895497308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.