ReviewPediatric nephrology (Berlin, Germany)2019
Hypertensive crisis in children and adolescents.
Review in Pediatric nephrology (Berlin, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Posterior reversible leukoencephalopathy syndrome associated with acute postinfectious glomerulonephritis: systematic review.Pediatric nephrology (Berlin, Germany) · 2022Pooled it
- Knowledge gaps and future directions in cognitive functions in children and adolescents with primary arterial hypertension: A systematic review.Frontiers in cardiovascular medicine · 2022Pooled it
- Predictive factors for hypertensive encephalopathy in hospitalized pediatric patients: a retrospective case-control study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Perioperative Management of Paediatric Hypertension.Children (Basel, Switzerland) · 2025Review
- Clinical characteristics and outcomes of children with hypertensive encephalopathy.BMC pediatrics · 2025Article
- Efficacy and safety of fenoldopam for the treatment of hypertensive crises in children with kidney disease: a retrospective study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Benzyl alcohol improves Ang II-induced vascular and renal injury.Turkish journal of medical sciences · 2025Article
- Clinical guidelines for the diagnosis, evaluation, and management of hypertension for Korean children and adolescents: the Korean Working Group of Pediatric Hypertension.Kidney research and clinical practice · 2025Article
- Association of health behaviors in life's essential 8 and hypertension in adolescents: a cross-sectional study from the NHANES database.BMC cardiovascular disorders · 2024Article
- Association of magnesium deficiency, tobacco smoke exposure and hypertension in children and adolescents: evidence from the NHANES 2007-2018.BMC pediatrics · 2024Article
- Sociodemographic Associations With Blood Pressure in 10-14-Year-Old Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024Article
- Prevention and management of hypertensive crises in children with pheochromocytoma and paraganglioma.Frontiers in endocrinology · 2024Review
- Treatment of Hypertension in Children.Current hypertension reviews · 2024Review
- Prevalence of modifiable risk factors for cardiovascular disease among school-going children and adolescents in Eldoret, Kenya.The Pan African medical journal · 2024Article
- A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia.Clinical case reports · 2023Article
- Managing severe hypertension in children.Pediatric nephrology (Berlin, Germany) · 2023Review
- Outcomes of percutaneous transluminal renal angioplasty for pediatric renovascular hypertension: a 12-year retrospective single-center experience.Translational pediatrics · 2023Article
- Acute Ocular Complications after Recently Diagnosed Goodpasture's Syndrome - An Unusual Case of Hypertensive Retinopathy.Klinische Monatsblatter fur Augenheilkunde · 2023Article
- Clinical Characteristics of Hospitalized Pediatric Patients With Hypertensive Crisis-A Retrospective, Single-Center Study in China.Frontiers in cardiovascular medicine · 2022Article
- Management of Hypertensive Crises in Children: A Review of the Recent Literature.Frontiers in pediatrics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertensive crisis is a relatively rare condition in children. However, if not treated, it might be life-threatening and lead to irreversible damage of vital organs. Clinical presentation of patients with hypertensive crisis can vary from very mild (hypertensive urgency) to severe symptoms (hypertensive emergency) despite similarly high blood pressure (BP). Individualized assessment of patients presenting with high BP with emphasis on the evaluation of end-organ damage rather than on the specific BP number is a key in guiding physician's initial management of a hypertensive crisis. The main aim of the treatment of hypertensive crisis is the prevention or treatment of life-threatening complications of hypertension-induced organ dysfunction, including neurologic, ophthalmologic, renal, and cardiac complications. While the treatment strategy must be directed toward the immediate reduction of BP to reduce the hypertensive damage to these organs, it should not be at a too fast rate to cause hypoperfusion of vital organs by an excessively rapid reduction of BP. Thus, intravenous continuous infusions rather than intravenous boluses of antihypertensive medications should be the preferable mode of initial treatment of children with hypertensive emergency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.