Evidence map›Paper›PMID 30276514›Full record

ArticleClinical oral investigations2019

Postoperative morbidity of free flaps in head and neck cancer reconstruction: a report regarding 215 cases.

Maria Poisson, Julie Longis, Matthias Schlund, Morgane Pere, Guillaume Michel, Antoine Delagranda, François Mouawad, Benoit Piot, Hélios Bertin

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Enhanced recovery after surgery (ERAS) protocol improves patient outcomes in free flap surgery for head and neck cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Maria PoissonService de Chirurgie Maxillo-faciale et Stomatologie, CHU de Nantes, 1 place Alexis Ricordeau, 44093, Nantes Cedex 1, France. mariapoisson@free.fr.
Julie LongisService de Chirurgie Maxillo-faciale et Stomatologie, CHU de Nantes, 1 place Alexis Ricordeau, 44093, Nantes Cedex 1, France.
Matthias SchlundService de chirurgie Maxillo-faciale et Stomatologie, Hôpital Roger Salengro, CHRU Lille, rue du Pr. Emile Laine, 59037, Lille Cedex, France.
Morgane PereService de Biostatistiques, CHU de Nantes-Direction de la Recherche, 1 place Alexis Ricordeau, 44093, Nantes Cedex 1, France.
Guillaume MichelService d'ORL et Chirurgie Cervico-faciale, CHU de Nantes, 1 place Alexis Ricordeau, 44093, Nantes Cedex 1, France.
Antoine DelagrandaService d'ORL et Chirurgie Cervico-faciale, CHU Félix Guyon, 2 rue des Topazes, 97400, Saint-Denis, France.
François MouawadService d'ORL et Chirurgie Cervico-faciale, Hôpital Huriez CHRU de Lille, Inserm U908lab research, rue Michel Polonovski, 59000, Lille, France.
Benoit PiotService de Chirurgie Maxillo-faciale et Stomatologie, CHU de Nantes, 1 place Alexis Ricordeau, 44093, Nantes Cedex 1, France.
Hélios BertinService de Chirurgie Maxillo-faciale et Stomatologie, CHU de Nantes, 1 place Alexis Ricordeau, 44093, Nantes Cedex 1, France.
Centre Hospitalier Universitaire de Nantes · FRHôpital Claude Huriez · FRHôpital Roger Salengro · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to identify the factors responsible for free flap failure, the surgical complications, and the non-oral feeding period in patients treated for an oral squamous cell carcinoma. MATERIALS AND

methodsThis multicentric study included 215 patients treated by tumour resection with immediate free flap reconstruction for an OSCC between 2010 and 2016. All of the patient medical files were reviewed and the data regarding the patient medical history, the tumour-related features, the surgical procedure, and the postoperative recovery were compiled. A statistical analysis with univariate and multivariate logistic regression was carried out.

resultsThe free flap success rate was 94.4% in our series. A postoperative complication occurred in 101 patients (41%). Minor surgical complications were shown to increase the free flap failure rate (OR 3.32; p = 0.04). A major surgical complication was encountered in 48 patients (22.3%), and these were linked to minor surgical complications (OR 2.89; p = 0.004) and the use of a tracheostomy (OR 5.76, p = 0.002). Conversely, a medical history of high blood pressure had a protective effect (p = 0.04). The non-oral feeding rate at the end of the hospital stay was 28.4%, and it correlated with the tracheostomy (p = 0.002), as well as the major and the minor surgical complications (p = 0.04). CONCLUSION-CLINICAL RELEVANCE: Free flap reconstruction is a safe and reliable technique with head and neck cancer reconstruction. Postoperative care favouring early and safe oral-feeding, and avoiding a tracheostomy can reduce the incidence of surgical complications after OSCC reconstruction.

Indexed as

Plastic Surgery ProceduresCarcinoma, Squamous CellFree Tissue FlapsHead and Neck NeoplasmsHumansLogistic ModelsMorbidityMouth NeoplasmsMultivariate AnalysisPostoperative ComplicationsRetrospective StudiesTreatment OutcomeAdverse effectsHead and neck neoplasmReconstructive surgical procedureSurgical flapsTracheostomy

Identifiers

PMID30276514
OpenAlexW2894947564

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.